LEADER 03053nam  2200493   450 
001 9910717370303321
005 20221027044711.0
035   $a(CKB)2670000000429529
035   $a(NjHacI)992670000000429529
035   $a(OCoLC)806430496
035   $a(EXLCZ)992670000000429529
100   $a20221027d2012      uy             0
101 0 $aeng
135   $aur|||||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aComparative effectiveness of warfarin and newer oral anticoagulants for the long-term prevention and treatment of arterial and venous thromboembolism /$finvestigators, Soheir S. Adam [and four others]
210  1$aWashington, DC :$cDepartment of Veterans Affairs, Health Services Research and Development Service,$d[2012]
210  4$dİ2012
215   $a1 online resource (iv, 115 pages) $cillustrations
225 1 $aEvidence-Based Synthesis Program
300   $a"Evidence-based synthesis program."
300   $a"April 2012."
320   $aIncludes bibliographical references.
330 3 $aThe Veterans Health Administration (VHA) System serves a largely older, male population with a high prevalence of chronic atrial fibrillation (AF) and venous thromboembolism (VTE). Many veterans with chronic AF have risk profiles for stroke that, according to current clinical guidelines, place them in a risk group where chronic anticoagulation is recommended. Adjusted-dose warfarin has been the preferred approach to chronic anticoagulation in the VHA, and in many VHA settings, specialized therapeutic drug-monitoring services provide high-quality warfarin treatment. However, the advent of newer anticoagulants with the promise of simplified long-term anticoagulation requires reconsideration of current treatment practices. The purpose of this systematic review was to study the comparative effectiveness of warfarin and the newer oral anticoagulants used for the long-term prevention and treatment of arterial and venous thromboembolism. An evaluation of newer oral anticoagulants for VTE prophylaxis in the perioperative period will be the subject of a later report.
410  0$aEvidence-based synthesis program (Series)
606   $aThromboembolism
607   $aUnited States$2fast
608   $aTechnical reports.$2lcgft
615  0$aThromboembolism.
676   $a616.145
700   $aAdam$b Soheir S.$01353454
702   $aAdam$b Soheir S.
712 02$aUnited States.$bDepartment of Veterans Affairs.$bHealth Services Research and Development Service,
712 02$aDurham VA Medical Center.$bEvidence-based Synthesis Program Center.
712 02$aQuality Enhancement Research Initiative (U.S.)
712 02$aEvidence-based Synthesis Program (U.S.)
801  0$bNjHacI
801  1$bNjHacl
906   $aBOOK
912   $a9910717370303321
996   $aComparative effectiveness of warfarin and newer oral anticoagulants for the long-term prevention and treatment of arterial and venous thromboembolism$93498644
997   $aUNINA