LEADER 00879nam0-22002891i-450- 001 990004186170403321 005 19990530 035 $a000418617 035 $aFED01000418617 035 $a(Aleph)000418617FED01 035 $a000418617 100 $a19990530g19609999km-y0itay50------ba 101 0 $ager 105 $ay-------00-y- 200 1 $a<>epirrhematische Agon bei Aristophanes$eUntersuchungen Alten Komödie$fCarl Thomas Gelzer 210 $aMünchen$cC.H.Beck'sche$d1960 215 $aXIII, 296 p.$d24 cm 225 1 $aZetemata$v23 700 1$aGelzer,$bCarl Thomas$0163789 702 1$aAristophanes$f 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990004186170403321 952 $aFCL 409 (23)$bIst.Fil.Cl.67$fFLFBC 959 $aFLFBC 996 $aEpirrhematische Agon bei Aristophanes$9485290 997 $aUNINA LEADER 01101cam a2200241 i 4500 001 991000984739707536 008 050422s2003 it aa 000 0 ita d 020 $a2717722327 035 $ab13302863-39ule_inst 040 $aDip.to Beni Culturali $bita 110 2 $aBibliothèque nationale (Francia).$bDépartement des monnaies, médailles et antiques$0622202 245 10$aSylloge Nummorum Graecorum:$bFrance 6,1 Département de monnaies, medailles et antiques. 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February 5, 1926. -- Committed to the Committee of the Whole House on the State of the Union and ordered to be printed 210 1$a[Washington, D.C.] :$c[U.S. Government Printing Office],$d1926. 215 $a1 online resource (3 pages) 225 1 $aHouse report / 69th Congress, 1st session. House ;$vno. 203 225 1 $a[United States congressional serial set ] ;$v[serial no. 8531] 300 $aBatch processed record: Metadata reviewed, not verified. Some fields updated by batch processes. 300 $aFDLP item number not assigned. 606 $aBuilding 606 $aDisaster relief 606 $aFood relief 606 $aHurricanes 606 $aPublic works 606 $aRoads$xDesign and construction 608 $aLegislative materials.$2lcgft 615 0$aBuilding. 615 0$aDisaster relief. 615 0$aFood relief. 615 0$aHurricanes. 615 0$aPublic works. 615 0$aRoads$xDesign and construction. 701 $aCoolidge$b Calvin$f1872-1933.$01386178 701 $aMcClintic$b James Vernon$f1878-1948$pDemocrat (OK)$01403180 712 02$aUnited States.$bPresident (1923-1929 : Coolidge) 712 02$aUnited States.$bDepartment of the Treasury.$bBureau of the Budget (1921-1939) 801 0$bWYU 801 1$bWYU 801 2$bOCLCO 801 2$bOCLCQ 906 $aBOOK 912 $a9910716259803321 996 $aAuthorizing an appropriation of$93475248 997 $aUNINA LEADER 04628nam 22006735 450 001 9910416108503321 005 20251113204345.0 010 $a981-15-5652-0 024 7 $a10.1007/978-981-15-5652-4 035 $a(CKB)4100000011343398 035 $a(DE-He213)978-981-15-5652-4 035 $a(MiAaPQ)EBC6272252 035 $a(PPN)260303623 035 $a(MiAaPQ)EBC6264051 035 $a(EXLCZ)994100000011343398 100 $a20200710d2020 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGM3 Signaling /$fby Cheorl-Ho Kim 205 $a1st ed. 2020. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2020. 215 $a1 online resource (VII, 138 p. 32 illus., 26 illus. in color.) 311 08$a981-15-5651-2 327 $a1. History of sialic acids, gangliosides and GM3 -- 2. Synthesis of GM3 -- 3. Molecular localization of GM3 in cells -- 4. Basic function of GM3 as an interacting molecule -- 5. GD3 mimetics with a neurite forming capacity -- 6. GM3 as a pathogenic infection receptor -- 7. GM3 and related gangliosides prevent inflammation and atherosclerosis -- 8. GM3 has an anti-tumor capacity -- 9. GM3 suppresses tumor angiogenesis -- 10. Interaction between EGFR and GM3 -- 11. Membrane ganglioside-specific neuraminidase 3 (NEU3) regulates GM3 signaling -- 12. Regulation of GM3-mediated EGFR signaling by NEU3 sialidase -- 13. VEGFR-GM3 interaction in angiogenesis -- 14. GM3, competing with GM1, interaction with urokinase plasminogen activator receptor (uPAR) in endothelial caveolar-lipid rafts inhibits angiogenesis -- 15. GM3 interacts with TGF? Rs in the epithelial-mesenchymal transition (EMT) during posterior capsular opacification (PCO) formation -- 16. Galectin-1 promotes tumor growth and escapes immune surveillance -- 17. GM3-HGFR, FGFR and PDGFR cancer cell behavior, and IGF-1R in diabetic wound healing -- 18. GM3, caveolin-1 and insulin receptor in insulin resistance -- 19. GM3 suppresses arthritis -- 20. GM3 protects cochlear hair cells and hearing from corti degeneration -- 21. GM3 increases osteoclast differentiation via direct GM3 cooperation with RANKL and IGF-1 -- 22. GM3 in leukemic cells into terminal differentiation -- 23. ?2,3-Sialyllactose (3SL) or ?2,6-sialyllactose (6SL) of GM3 glycan in innate immunity. . 330 $aThis book reviews recent progress in understanding of the signaling and biochemistry of GM3 ganglioside in eukaryotic cells. GM3 is the simplest of the gangliosides and the precursor of other gangliosides. It is expressed in the outer leaflet of plasma cell membranes and has roles in the recognition, interaction, binding, adhesion, and motility of cells. In addition, GM3 has been documented to have functional roles in cell migration, proliferation, senescence, and apoptosis. The full range of topics of interest are addressed in the book. The early chapters discuss the synthesis of GM3, its molecular localization in cells, and its basic function as an interacting molecule. The ways in which GM3 exerts its effects via various growth factor receptors are fully explored. Current knowledge of the part played by GM3 in health and disease is discussed in depth. For example, its roles in preventing inflammation, inhibiting tumor angiogenesis and tumor growth, and suppressing arthritis are highlighted, and attention drawn to the significance of GM3 as a driver of impaired wound healing in diabetics. The book will be of interest to all who want a comprehensive update on research in this field. 606 $aMolecular genetics 606 $aCancer 606 $aGenetics 606 $aBiochemistry 606 $aBiological transport 606 $aCell membranes 606 $aMolecular Genetics 606 $aCancer Biology 606 $aGenetics and Genomics 606 $aBiochemistry 606 $aMembrane Trafficking 615 0$aMolecular genetics. 615 0$aCancer. 615 0$aGenetics. 615 0$aBiochemistry. 615 0$aBiological transport. 615 0$aCell membranes. 615 14$aMolecular Genetics. 615 24$aCancer Biology. 615 24$aGenetics and Genomics. 615 24$aBiochemistry. 615 24$aMembrane Trafficking. 676 $a378.1662 700 $aKim$b Cheorl-Ho$4aut$4http://id.loc.gov/vocabulary/relators/aut$01062709 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910416108503321 996 $aGM3 Signaling$92546180 997 $aUNINA