LEADER 05398nam 2200673Ia 450 001 9910144323603321 005 20170810192820.0 010 $a1-280-85420-0 010 $a9786610854202 010 $a3-527-60754-4 010 $a3-527-60712-9 035 $a(CKB)1000000000376400 035 $a(EBL)481674 035 $a(OCoLC)70048393 035 $a(SSID)ssj0000175535 035 $a(PQKBManifestationID)11156097 035 $a(PQKBTitleCode)TC0000175535 035 $a(PQKBWorkID)10204132 035 $a(PQKB)11608884 035 $a(MiAaPQ)EBC481674 035 $a(EXLCZ)991000000000376400 100 $a20050519d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aHydrolases in organic synthesis$b[electronic resource] $eregio- and stereoselective biotransformations /$fUwe T. Bornscheuer and Romas J. Kazlauskas 205 $a2nd ed. 210 $aWeinheim $cWiley-VCH ;$aChichester $cJohn Wiley$dc2006 215 $a1 online resource (369 p.) 300 $aDescription based upon print version of record. 311 $a3-527-31029-0 320 $aIncludes bibliographical references and index. 327 $aHydrolases in Organic Synthesis; Preface for the 2(nd) edition; Preface for the 1(st) edition; Acknowledgments; Contents; 1 Introduction; 2 Designing Enantioselective Reactions; 2.1 Kinetic Resolutions; 2.1.1 Recycling and Sequential Kinetic Resolutions; 2.1.2 Dynamic Kinetic Resolutions; 2.1.2.1 Introduction; 2.1.2.2 Racemization by Protonation/Deprotonation; 2.1.2.3 Racemization by Addition/Elimination; 2.1.2.4 Racemization by Nucleophilic Substitution; 2.1.2.5 Racemization by Oxidation/Reduction; 2.1.2.6 Related Strategies; 2.2 Asymmetric Syntheses 327 $a3 Choosing Reaction Media: Water and Organic Solvents3.1 Hydrolysis in Water; 3.2 Transesterifications and Condensations in Organic Solvents; 3.2.1 Increasing the Catalytic Activity in Organic Solvents; 3.2.1.1 Choosing the Best Organic Solvent for High Activity; 3.2.2 Increasing the Enantioselectivity in Organic Solvents; 3.2.3 Water Content and Water Activity; 3.3 Other Reaction Media; 3.3.1 Ionic Liquids; 3.3.2 Reverse Micelles; 3.3.3 Supercritical Fluids; 3.4 Immobilization; 3.4.1 Introduction; 3.4.1.1 Increasing the Surface Area to Increase Catalytic Activity 327 $a4 Protein Sources and Optimization of Biocatalyst Performance4.1 Accessing Biodiversity; 4.2 Creating Improved Biocatalysts; 4.2.1 Directed Evolution; 4.2.1.1 Methods to Create Mutant Libraries; 4.2.1.2 Assay Systems; 4.2.1.3 Selected Examples; 4.2.2 Focused Directed Evolution; 4.3 Catalytic Promiscuity in Hydrolases; 4.3.1 Reactions Involving Functional Group Analogs; 4.3.1.1 Perhydrolases; 4.3.2 Aldol and Michael additions Catalyzed by Hydrolases; 4.3.2.1 Aldol Additions; 4.3.2.2 Michael-Type Additions; 4.3.3 Modifications to Introduce New Reactivity in Hydrolases 327 $a4.3.3.1 Enantioselective Reduction of Hydroperoxides with Selenosubtilisin4.3.3.2 Vanadate-Modified Phosphatases as Peroxidases; 5 Lipases and Esterases; 5.1 Availability, Structures and Properties; 5.1.1 Lipases; 5.1.1.1 Classification of Lipases; 5.1.1.2 General Features of PPL, PCL, CRL, CAL-B, and RML; 5.1.2 Esterases; 5.1.3 Lipases and Esterases are ?/? Hydrolases; 5.1.4 Lid or Flap in Interfacial Activation of Lipases; 5.1.5 Substrate Binding Site in Lipases and Esterases; 5.1.6 Designing Reactions with Lipases and Esterases; 5.1.6.1 Acyl Donor for Acylation Reactions 327 $a5.1.7 Assays for Lipases and Esterases5.1.7.1 Requirements for a Suitable Assay; 5.1.7.2 How to Distinguish Between Lipase, Esterase, and Protease; 5.2 Survey of Enantioselective Lipase-Catalyzed Reactions; 5.2.1 Alcohols; 5.2.1.1 Secondary Alcohols; 5.2.1.2 Primary Alcohols; 5.2.1.3 Other Alcohols, Amines, and Alcohol Analogs; 5.2.2 Carboxylic Acids; 5.2.2.1 General Considerations; 5.2.2.2 Carboxylic Acids with a Stereocenter at the ?-Position; 5.2.2.3 Carboxylic Acids with a Stereocenter at the ?-Position; 5.2.2.4 Other Carboxylic Acids; 5.2.2.5 Double Enantioselection; 5.2.2.6 Anhydrides 327 $a5.2.3 Lactones 330 $aFrom reviews to the first edtion:""Bornscheuer and Kazlauskas have set out, and succeeded, in producing a definitive manual on hydrolytic enzymes (especially lipases, esterases, and proteases) for organic chemists. This is quite simply the best book of its type and can be unreservedly recommended to organic chemists who have an interest in using hydrolytic enzymes in synthesis."" (Nicholas J. Turner, University of Edinburgh)""The book is an indispensable source of information on the use of hydrolases in organic synthesis. The subject matter is very well set out, and the chapter 606 $aCatalysis 606 $aHydrolases 606 $aOrganic compounds$xSynthesis 608 $aElectronic books. 615 0$aCatalysis. 615 0$aHydrolases. 615 0$aOrganic compounds$xSynthesis. 676 $a547.2 686 $a35.74$2bcl 700 $aBornscheuer$b U. T$g(Uwe Theo),$f1964-$0968009 701 $aKazlauskas$b R. J$g(Romas J.),$f1956-$0886693 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910144323603321 996 $aHydrolases in organic synthesis$92198463 997 $aUNINA LEADER 04148nam a2200373Ii 4500 001 991003259239707536 006 m d 007 cr cn||||||||| 008 070806s2003 mau s 000 u eng d 020 $a9781931836975 020 $a1931836973 035 $ab13656612-39ule_inst 037 $a100746:100752$bElsevier Science & Technology$nhttp://www.sciencedirect.com 040 $aOPELS$cOPELS 049 $aTEFA 082 04$a005.8$222 245 00$aCheck Point NG VPN-1/Firewall-1$h[electronic resource] :$badvanced configuration and troubleshooting /$cJim Noble ...[et. a.]. 260 $aRockland, Mass. :$bSyngress,$c2003. 300 $axxxi, 606 p. 520 $aCheck Point Software Technologies is the worldwide leader in securing the Internet. The company's Secure Virtual Network (SVN) architecture provides the infrastructure that enables secure and reliable Internet communications. Check Point recently announced a ground-breaking user interface that meets the industry's next generation Internet security requirements, including simplified security management for increasingly complex environments. Built upon Check Point's Secure Virtual Network (SVN) architecture, the Next Generation User Interface revolutionizes the way security administrators define and manage enterprise security by further integrating management functions into a security dashboard and creating a visual picture of security operations. The Next Generation User Interface delivers unparalleled ease-of-use, improved security and true end-to-end security management. Check Point's revenues have more than doubled in each of the last two years, while capturing over 50% of the VPN market and over 40% of the firewall market according to IDC Research. The explosive growth of the company is further evidenced by over 29,000 IT professionals becoming Check Point Certified so far. This book will be the complimentary to Syngress' best-selling Check Point Next Generation Security Administration, which was a foundation-level guide to installing and configuring Check Point NG. This book will assume that readers have already mastered the basic functions of the product and they now want to master the more advanced security and VPN features of the product. Written by a team of Check Point Certified Instructors (the most prestigious Check Point certification) this book will provide readers with a complete reference book to Check Point NG and advanced case studies that illustrate the most difficult to implement configurations. Although not a Study Guide, this book will cover all of the objectives on Check Point's CCSE Exam. The reader will learn to design and configure a Virtual Private Network (VPN). The reader will learn to configure Check Point NG for High Availability (HA), which is the ability of a system to perform its function continuously (without interruption) for a significantly longer period of time than the reliabilities of its individual components would suggest. The reader will learn to use SeucureUpdate, which allows them to perform simultaneous, secure, enterprise-wide software updates. 533 $aElectronic reproduction.$bAmsterdam :$cElsevier Science & Technology,$d2007.$nMode of access: World Wide Web.$nSystem requirements: Web browser.$nTitle from title screen (viewed on Aug. 2, 2007).$nAccess may be restricted to users at subscribing institutions. 650 0$aComputer security$xComputer programs. 650 0$aFirewalls (Computer security) 650 0$aComputer networks$xSecurity measures$xComputer programs. 655 7$aElectronic books.$2local 700 1 $aNoble, Jim.$eauthor$4http://id.loc.gov/vocabulary/relators/aut$0739086 776 1 $cOriginal$z1931836973$z9781931836975$w(OCoLC)70742413 856 40$3Referex$uhttp://www.sciencedirect.com/science/book/9781931836975$zAn electronic book accessible through the World Wide Web; click for information 907 $a.b13656612$b24-02-22$c24-01-08 912 $a991003259239707536 994 $aC0$bTEF 996 $aCheck Point NG VPN-1$91464041 997 $aUNISALENTO 998 $ale029$b24-01-08$cm$dm $e-$feng$gmau$h0$i0 LEADER 02048oam 2200529 450 001 9910707619003321 005 20161014150110.0 035 $a(CKB)5470000002466352 035 $a(OCoLC)886546887 035 $a(EXLCZ)995470000002466352 100 $a20140812d1973 ua 0 101 0 $aeng 135 $aurbn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aStratigraphic divisions and geologic history of the Laney Member of the Green River Formation in the Washakie Basin in southwestern Wyoming /$fby Henry W. Roehler 210 1$a[Washington, D.C.] :$cUnited States Department of the Interior, Geological Survey,$d1973. 210 2$aWashington :$cUnited States Government Printing Office. 215 $a1 online resource (iii, 28 pages) $cillustrations, maps 225 1 $aGeological Survey bulletin ;$v1372-E 225 1 $aContributions to stratigraphy. Geological Survey bulletin 1372-E 300 $aTitle from title screen (viewed August 4, 2014). 300 $a"The Laney Member is divided into the Hartt Cabin, Sand Butte, and LaClede Beds." 320 $aIncludes bibliographical references (pages 27-28). 606 $aGeology, Stratigraphic$yEocene 606 $aGeology$zWyoming$zSweetwater County 606 $aEocene Geologic Epoch$2fast 606 $aGeology$2fast 606 $aGeology, Stratigraphic$2fast 607 $aWyoming$zSweetwater County$2fast 615 0$aGeology, Stratigraphic 615 0$aGeology 615 7$aEocene Geologic Epoch. 615 7$aGeology. 615 7$aGeology, Stratigraphic. 700 $aRoehler$b Henry W.$01392979 712 02$aGeological Survey (U.S.), 801 0$bCOP 801 1$bCOP 801 2$bOCLCO 801 2$bOCLCF 801 2$bGPO 906 $aBOOK 912 $a9910707619003321 996 $aStratigraphic divisions and geologic history of the Laney Member of the Green River Formation in the Washakie Basin in southwestern Wyoming$93538627 997 $aUNINA