LEADER 01083nam0-2200373---450- 001 990009166300403321 005 20120323102923.0 010 $a978-1-4129-6897-3 035 $a000916630 035 $aFED01000916630 035 $a(Aleph)000916630FED01 035 $a000916630 100 $a20100329d2010----km-y0itaa50------ba 101 0 $aeng 102 $aUS 105 $a--------001yy 200 1 $aMultiple correspondence analysis$fBrigitte Le Roux, Henry Rouanet 210 $aThousand Oaks$cSAGE Publications, Inc.$d2010 215 $ax, 115 p.$d22 cm 225 1 $aQuantitative applications in the social sciences$v163 610 0 $aStatistica 610 0 $aAnalisi delle corrispondenze 676 $a519.5 700 1$aLe Roux,$bBrigitte$0103514 701 1$aRouanet,$bHenry$0102476 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990009166300403321 952 $aXXIX-D-158$b11140$fMAS 952 $a10810 SAG/163$b407/DEC$fSES 959 $aMAS 959 $aSES 996 $aMultiple correspondence analysis$9780300 997 $aUNINA LEADER 01844oam 2200433I 450 001 9910707274303321 005 20240201233212.0 035 $a(CKB)5470000002462763 035 $a(OCoLC)891382644 035 $a(EXLCZ)995470000002462763 100 $a20140926d1969 ua 0 101 0 $aeng 135 $aurmn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGeology of the Oregon Buttes area, Sweetwater, Sublette and Fremont Counties, southwestern Wyoming $eInvestigations of an area that includes South Pass, where the historic Emigrant Trail crosses the Continental Divide /$fby H.D. Zeller and E.V. Stephens 210 1$a[Washington, D.C.] :$cUnited States Department of the Interior, Geological Survey,$d1969. 210 2$aWashington :$cUnited States Government Printing Office. 215 $a1 online resource (iv, 60 pages, 2 pages of plates) $cillustrations, maps (some color) 225 1 $aGeological Survey bulletin ;$v1256 300 $aTitle from title screen (viewed September 15, 2014). 320 $aIncludes bibliographical references (pages 55-58) and index. 517 $aGeology of the Oregon Buttes area, Sweetwater, Sublette and Fremont Counties, southwestern Wyoming 606 $aGeology$zWyoming$zOregon Buttes Wilderness 606 $aBorings$zWyoming$zOregon Buttes Wilderness 615 0$aGeology 615 0$aBorings 700 $aZeller$b H. D$g(Howard Davis),$f1922-2009,$01587235 702 $aStephens$b E. V. 712 02$aGeological Survey (U.S.), 801 0$bCOP 801 1$bCOP 801 2$bOCLCO 801 2$bGPO 906 $aBOOK 912 $a9910707274303321 996 $aGeology of the Oregon Buttes area, Sweetwater, Sublette and Fremont Counties, southwestern Wyoming$93876584 997 $aUNINA LEADER 02803nam 22004935 450 001 9910349445703321 005 20200703082634.0 010 $a981-329-267-9 024 7 $a10.1007/978-981-32-9267-3 035 $a(CKB)4100000009152993 035 $a(MiAaPQ)EBC5889019 035 $a(DE-He213)978-981-32-9267-3 035 $a(PPN)242824277 035 $a(EXLCZ)994100000009152993 100 $a20190830d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aSIRT6 Activities in DNA Damage Repair and Premature Aging $eFunctions of SIRT6 /$fby Shrestha Ghosh 205 $a1st ed. 2019. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2019. 215 $a1 online resource (188 pages) 225 1 $aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053 300 $a"Doctoral thesis accepted by The University of Hong Kong, Hong Kong, China"--Title page. 311 $a981-329-266-0 327 $aIntroduction -- Materials and Methods -- Results-I. Lamin A is an endogenous activator of SIRT6 in DNA damage repair process -- Results-II. Haploinsufficiency of p53 rescues lifespan and premature aging-associated abnormalities in Sirt6-deficient mice -- Results-III. SIRT6 is an acetylated protein and a NAD+-dependent self-deacetylase -- Discussion. 330 $aThis book illustrates the activities of mammalian sirtuin SIRT6 in connection with DNA damage repair and premature aging. It mainly presents research on the nuclear lamin A, notably the upregulation of p53 and acetylation etc. Taken together, these studies reveal the various regulatory roles of SIRT6, which are of substantial biological relevance in DNA damage repair, aging and longevity, and can have significant implications in devising therapeutic strategies to combat age-associated pathologies. Given its scope, the book offers a valuable resource for students and researchers in the fields of genetics, cell biology, molecular biology etc. 410 0$aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053 606 $aHuman genetics 606 $aCytology 606 $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008 606 $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008 615 0$aHuman genetics. 615 0$aCytology. 615 14$aHuman Genetics. 615 24$aCell Biology. 676 $a572.86459 700 $aGhosh$b Shrestha$4aut$4http://id.loc.gov/vocabulary/relators/aut$0963288 906 $aBOOK 912 $a9910349445703321 996 $aSIRT6 Activities in DNA Damage Repair and Premature Aging$92184141 997 $aUNINA