LEADER 01648oam 2200409 450 001 9910704161703321 005 20161019104400.0 035 $a(CKB)5470000002438047 035 $a(OCoLC)930704782 035 $a(EXLCZ)995470000002438047 100 $a20151201d2015 ua 0 101 0 $aeng 135 $aurbn||||a|||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aSearching for the origins of the universe $ean update on the progress of the James Webb Space Telescope : hearing before the Subcommittee on Space, Committee on Science, Space, and Technology, House of Representatives, One Hundred Fourteenth Congress, first session, March 24, 2015 210 1$aWashington :$cU.S. Government Publishing Office,$d2015. 215 $a1 online resource (iv, 162 pages) $cillustrations 300 $aTitle from title screen (viewed on Dec. 1, 2015). 300 $aPaper version available for sale by the Superintendent of Documents, U.S. Government Publishing Office. 300 $a"Serial No. 114-11." 320 $aIncludes bibliographical references. 517 $aSearching for the origins of the universe 606 $aOrbiting astronomical observatories 606 $aAstrophysics$xResearch$zUnited States 607 $aOuter space$xExploration 608 $aLegislative hearings.$2lcgft 615 0$aOrbiting astronomical observatories. 615 0$aAstrophysics$xResearch 801 0$bGPO 801 1$bGPO 801 2$bGPO 906 $aBOOK 912 $a9910704161703321 996 $aSearching for the origins of the universe$93502288 997 $aUNINA LEADER 03439nam 22006735 450 001 9910736984503321 005 20251008163434.0 010 $a9789811974199 010 $a9811974195 024 7 $a10.1007/978-981-19-7419-9 035 $a(MiAaPQ)EBC30674564 035 $a(CKB)27922755700041 035 $a(Au-PeEL)EBL30674564 035 $a(DE-He213)978-981-19-7419-9 035 $a(PPN)272269352 035 $a(OCoLC)1392340343 035 $a(EXLCZ)9927922755700041 100 $a20230803d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEpigenetic Mechanisms of Cell Programming and Reprogramming /$fedited by Gang Pei 205 $a1st ed. 2023. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2023. 215 $a1 online resource (68 pages) 225 1 $aReports of China?s Basic Research,$x2731-8915 311 0 $a9789811974182 327 $a1. Project Overview -- 2. Domestic and Foreign Research -- 3. Major Research Achievements -- 4.Outlook. 330 $aThis book presents a major research program on epigenetic mechanisms of cell programming and reprogramming. The program was launched by the National Natural Science Foundation of China during the 11th Five-Year Plan period, which was started in October 2008 and concluded at the end of 2016. It first summarizes the epigenetic research plans and the current situation of epigenetic research in China and the international frontier. With the application of interdisciplinary research methods, the book discusses the development trends of epigenetic research, such as mechanisms of establishment and maintenance of epigenetic information and epigenetic regulation on reproduction and development. It also presents a variety of research achievements. For example, the discovery of new epigenetic regulators and chromatin remodulaters and their biological functions and mechanisms are highlighted. Several regulation mechanisms of cell differentiation and trans-differentiation are discussed, especially the discovery of the key factors to promote the trans-differentiation of somatic cells to hepatocytes. In addition, this book puts forward some key academic fields with increasing importance, such as biochemistry, cell biology, and clinical medicine. Given its scope, the book is of interest to researchers who work in cell biology, biochemistry, structural biology, bioinformatics, clinical medicine, and other related fields. . 410 0$aReports of China?s Basic Research,$x2731-8915 606 $aBiochemistry 606 $aCytology 606 $aMedical genetics 606 $aBiomaterials 606 $aNucleic acids 606 $aBiochemistry 606 $aCell Biology 606 $aMedical Genetics 606 $aNucleic Acid 615 0$aBiochemistry. 615 0$aCytology. 615 0$aMedical genetics. 615 0$aBiomaterials. 615 0$aNucleic acids. 615 14$aBiochemistry. 615 24$aCell Biology. 615 24$aMedical Genetics. 615 24$aNucleic Acid. 676 $a572 701 $aPei$b Gang$01381736 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910736984503321 996 $aEpigenetic Mechanisms of Cell Programming and Reprogramming$93424586 997 $aUNINA