LEADER 01157nam 2200373 a 450 001 9910701017203321 005 20111229120214.0 035 $a(CKB)5470000002414869 035 $a(OCoLC)769764262 035 $a(EXLCZ)995470000002414869 100 $a20111229d2007 ua 0 101 0 $aeng 135 $aurmn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aAsbestos$b[electronic resource] $edo not disturb 210 1$aWashington, D.C. :$cOffice of Compliance,$d[2007] 215 $a1 online resource (2 unnumbered pages) $ccolor illustrations 225 1 $aFast facts 300 $a"September 2007." 300 $aTitle from title screen (viewed on Dec. 22, 2011). 517 $aAsbestos 606 $aAsbestos$xSafety measures 606 $aWork environment$zUnited States$xSafety measures 615 0$aAsbestos$xSafety measures. 615 0$aWork environment$xSafety measures. 712 02$aUnited States.$bOffice of Compliance. 801 0$bGPO 801 1$bGPO 906 $aBOOK 912 $a9910701017203321 996 $aAsbestos$91120593 997 $aUNINA LEADER 06384nam 2201969z- 450 001 9910346858503321 005 20210211 035 $a(CKB)4920000000095082 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/40775 035 $a(oapen)doab40775 035 $a(EXLCZ)994920000000095082 100 $a20202102d2019 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aAMP-Activated Protein Kinase Signalling 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2019 215 $a1 online resource (452 p.) 311 08$a3-03897-662-8 330 $aStarting from a kinase of interest, AMP-activated protein kinase (AMPK) has gone far beyond an average biomolecule. Being expressed in all mammalian cell types and probably having a counterpart in every eukaryotic cell, AMPK has attracted interest in virtually all areas of biological research. Structural and biophysical insights have greatly contributed to a molecular understanding of this kinase. From good old protein biochemistry to modern approaches, such as systems biology and advanced microscopy, all disciplines have provided important information. Thus, multiple links to cellular events and subcellular localizations have been established. Moreover, the crucial involvement of AMPK in human health and disease has been evidenced. AMPK accordingly has moved from an interesting enzyme to a pharmacological target. However, despite our extensive current knowledge about AMPK, the growing community is busier than ever. This book provides a snapshot of recent and current AMPK research with an emphasis on work providing molecular insight, including but not limited to novel physiological and pathological functions, or regulatory mechanisms. 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