LEADER 03629nam 2200577Ia 450 001 9910437850803321 005 20200520144314.0 010 $a1-283-84894-5 010 $a1-4614-4666-X 024 7 $a10.1007/978-1-4614-4666-8 035 $a(CKB)2670000000279087 035 $a(EBL)1030808 035 $a(OCoLC)824487129 035 $a(SSID)ssj0000789319 035 $a(PQKBManifestationID)11413147 035 $a(PQKBTitleCode)TC0000789319 035 $a(PQKBWorkID)10726479 035 $a(PQKB)10636383 035 $a(DE-He213)978-1-4614-4666-8 035 $a(MiAaPQ)EBC1030808 035 $a(PPN)168300877 035 $a(EXLCZ)992670000000279087 100 $a20121211d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAdvances in biology and therapy of multiple myeloma$hVolume 1$iBasic science /$fNikhil C. Munshi, Kenneth C. Anderson, editors 210 $aNew York $cSpringer$dc2013 215 $a1 online resource (321 p.) 300 $aDescription based upon print version of record. 311 $a1-4614-4665-1 320 $aIncludes bibliographical references and index. 327 $aGenomic strategies determining progressions from MGUS to Multiple Myeloma -- Prognostic implication of Genetic changes (Cytogenetics, and FISH, gains and losses of DNA by SNP array and aCGH) in risk stratification in myeloma -- Advances in MM gene expression profiling -- Growth factors in MM -- Role of Wnt signaling pathways in multiple myeloma pathogenesis -- mTOR pathway in multiple myeloma -- Jak/STAT signaling in the pathogenesis and treatment of multiple myeloma -- Role of extracellular matrix in myeloma biology -- Osteoclasts: Potential target for blocking microenvironmental support of myeloma -- Targeting the BAFF/APRIL cytokine network in multiple myeloma -- Role of Osteoblast in myeloma pathology -- Migration and homing in Multiple Myeloma -- Genes and proteins of myeloma endothelial cells to search specific targets of the tumor vasculature -- Epigenetic regulation of myeloma within its bone marrow microenvironment -- Targeting mulitple myeloma tumor angiogenesis: focus on VEGF -- Novel in vivo model in myeloma -- Index. 330 $aDespite the advances in conventional, and novel agent and high dose chemotherapy, multiple myeloma remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in multiple myeloma focusing on the development of molecularly-based novel targeted single-agent and combination therapies has great promise to achieve high frequency and durable responses in the majority of patients.   This volume will focus on biology of multiple myeloma, especially on oncogenomic changes, cell signaling pathways and intermediate molecules that are being investigated for development of novel therapies. The book will present newer developments, providing an emphasis on basic science, as well as its significant clinical impact. 606 $aBone marrow$xDiseases 606 $aMyelodysplastic syndromes 615 0$aBone marrow$xDiseases. 615 0$aMyelodysplastic syndromes. 676 $a616.99/418 676 $a616.9941806 701 $aMunshi$b Nikhil C$01064467 701 $aAnderson$b Kenneth C$0876632 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910437850803321 996 $aAdvances in biology and therapy of multiple myeloma$92538380 997 $aUNINA LEADER 01598nam 2200397Ia 450 001 9910699654003321 005 20240812224718.0 035 $a(CKB)5470000002404396 035 $a(OCoLC)690947972 035 $a(EXLCZ)995470000002404396 100 $a20101209d2010 ua 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aNutrient concentrations, loads, and yields in the Eucha-Spavinaw basin, Arkansas and Oklahoma, 2002-09 /$fby Rachel A. Esralew and Robert L. Tortorelli ; in cooperation with the City of Tulsa, Oklahoma 210 1$aReston, Va. :$cU.S. Geological Survey,$d2010. 215 $a1 online resource (vi, 61 pages) $ccolor illustrations, color maps 225 1 $aScientific investigations report ;$v2010-5119 300 $aTitle from PDF title screen (viewed on Dec. 9, 2010). 320 $aIncludes bibliographical references (pages 37-40). 410 0$aScientific investigations report ;$v2010-5119. 606 $aNutrient pollution of water$zEucha-Spavinaw Basin (Ark. and Okla.) 607 $aEucha-Spavinaw Basin (Ark. and Okla.) 615 0$aNutrient pollution of water 700 $aEsralew$b Rachel A$01395708 701 $aTortorelli$b Robert L$01388659 712 02$aTulsa (Okla.) 712 02$aGeological Survey (U.S.) 801 0$bGPO 801 1$bGPO 906 $aBOOK 912 $a9910699654003321 996 $aNutrient concentrations, loads, and yields in the Eucha-Spavinaw basin, Arkansas and Oklahoma, 2002-09$93503803 997 $aUNINA LEADER 04749nam 22006975 450 001 9910483000603321 005 20240509003531.0 010 $a9783030708498 010 $a3030708497 024 7 $a10.1007/978-3-030-70849-8 035 $a(CKB)4100000011902573 035 $a(MiAaPQ)EBC6567040 035 $a(Au-PeEL)EBL6567040 035 $a(OCoLC)1249471145 035 $a(DE-He213)978-3-030-70849-8 035 $a(EXLCZ)994100000011902573 100 $a20210422d2021 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHousing, Urban Commons and the Right to the City in Post-Crisis Rome $eMetropoliz, The Squatted Cittą Meticcia /$fby Margherita Grazioli 205 $a1st ed. 2021. 210 1$aCham :$cSpringer International Publishing :$cImprint: Palgrave Macmillan,$d2021. 215 $a1 online resource (175 pages) 311 08$a9783030708481 311 08$a3030708489 320 $aIncludes bibliographical references and index. 327 $a1. Introduction -- 2. Housing Squats, Urban Commons, Right to the City -- 3. The Activist Ethnographic Method -- 4. Rome, The Squatted City -- 5. Occupy Metropoliz -- 6. The Commoning and Eurythmization of the Cittą Meticcia -- 7. The Politics and Urban Commons of Metropoliz and the MAAM -- 8. Without Metropoliz, This Ain't My City!. 330 $a"Grazioli's nuanced and contextualised accounts of the 'housing squat' Metropoliz provide an illuminating discussion of the political value that concepts such as 'the right to the city' and 'urban commons' hold for contemporary anti-capitalist struggles." - Miguel A. Martķnez, author of Squatters in the Capitalist City, Uppsala University, Sweden "As a precise and passionate analytical account of the ways in which mundane built environments can be repurposed for the engendering of inventive forms of collective life, this book is an essential guide. In an era that makes constant reference to the commons, Grazioli vividly shows us just what such a commons concretely might be." - AbdouMaliq Simone, Urban Institute - University of Sheffield, UK "With her beautiful and powerful prose, Grazioli not only offers a grounded analysis of the meaning and makings of liberatory forms of housing, but she also shows what it means to researchspaces like Metropoliz embodying and reverberating their broader urban politics. This book is a quintessential read for anyone concerned with the future of cities well beyond Rome." - Michele Lancione, Urban Institute - University of Sheffield, UK This book tells the story of Metropoliz, a vacant salami factory located in the Eastern periphery of Rome (Italy) that was squatted in 2009 by homeless households with the cooperation of the Housing Rights Movement Blocchi Precari Metropolitani, and progressively reconverted into the house and museum spaces that form the Cittą Meticcia (the mestizo city). Through a vivid activist-ethnographic account, Margherita Grazioli suggests that Metropoliz exemplifies a practice of grassroots urban regeneration that speaks to the conflicted reconfiguration of real estate urban regimes in a post-crisis, post-neoliberal scenario. Using the contentious reappropriation of housing as a point of departure for claiming manifold rights, Metropoliz represents an alternative model of urbanity and habitation that will inspire contemporary urban social movements concerned with the demand of the 'right to the city', as well as those concerned with the ontology of the urban commons. Margherita Grazioli is Postdoctoral Research Fellow in Regional Sciences & Economic Geography at the Social Sciences Area of the Gran Sasso Science Institute in L'Aquila, Italy. 606 $aEthnology 606 $aHuman geography 606 $aSociology, Urban 606 $aSocial structure 606 $aEquality 606 $aSociocultural Anthropology 606 $aHuman Geography 606 $aEthnography 606 $aUrban Sociology 606 $aSocial Structure 615 0$aEthnology. 615 0$aHuman geography. 615 0$aSociology, Urban. 615 0$aSocial structure. 615 0$aEquality. 615 14$aSociocultural Anthropology. 615 24$aHuman Geography. 615 24$aEthnography. 615 24$aUrban Sociology. 615 24$aSocial Structure. 676 $a307.760945632 676 $a307.760945632 700 $aGrazioli$b Margherita.$0853473 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910483000603321 996 $aHousing, Urban Commons and the Right to the City in Post-Crisis Rome$91905758 997 $aUNINA