LEADER 05770nam 2200781Ia 450 001 9910698584903321 005 20230120010114.0 010 $a1-282-28540-8 010 $a9786612285400 010 $a0-08-091897-2 035 $a(CKB)1000000000555440 035 $a(EBL)365567 035 $a(OCoLC)476198582 035 $a(SSID)ssj0000113413 035 $a(PQKBManifestationID)11999931 035 $a(PQKBTitleCode)TC0000113413 035 $a(PQKBWorkID)10099155 035 $a(PQKB)11375468 035 $a(MiAaPQ)EBC365567 035 $a(EXLCZ)991000000000555440 100 $a20080818d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBluetongue$b[electronic resource] /$fedited by Philip S. Mellor, Matthew Baylis and Peter P.C. Mertens 205 $a1st ed. 210 $aAmsterdam ;$aBoston $cElsevier Academic Press$d2009 215 $a1 online resource (507 p.) 225 1 $aBiology of animal infections 300 $aDescription based upon print version of record. 311 $a0-12-369368-3 320 $aIncludes bibliographical references and index. 327 $aFront Cover; Bluetongue; Copyright Page; Contents; Series Introduction; Preface; Acknowledgement; Chapter 1 Introduction; Background; Bluetongue, an emerging disease; Chapter 2 The history of bluetongue; Introduction; Geographical distribution; Host range; Aetiology; Transmission; Control; Chapter 3 Bluetongue virus, other orbiviruses and other reoviruses: Their relationships and taxonomy; Introduction; The genera of the family Reoviridae; The genus Orbivirus; Classification and differentiation of the Orbivirus species; The economically important orbiviruses; Emerging orbiviruses 327 $aOrbiviruses that can infect humansRelationships with other reoviruses; Phylogenetic relationships of the orbivirus proteins; Phylogenetic relationships between the RNA- dependent RNA polymerase (Pol - RdRP) of the different orbiviruses; Phylogenetic relationships based on the sub-core shell T2 protein of bluetongue virus and other orbiviruses; Dating divergence times for bluetongue virus and epizootic haemorrhagic disease virus serotypes; Chapter 4 Bluetongue virus replication and assembly; Introduction; Arrangement of proteins in the virus outer capsid and their role in virus entry 327 $aFunctional dissection of the enzymatic core proteinsAssembly of the viral core; Assembly of the viral outer capsid; Release of progeny virions from infected cells; Concluding remarks; Chapter 5 Bluetongue virus: cell biology; Introduction; Bluetongue virus entry into the cellular host; Viral structures and their functions; Interaction of bluetongue virus with the cytoskeleton; Involvement of the cellular translation machinery during bluetongue virus infection; Fate of bluetongue virus-infected cells and virus egress; Conclusions; Chapter 6 The structure of bluetongue virus core and proteins 327 $aIntroductionThe bluetongue virion structure; Genome packaging; Enzyme functions and location; Substrate and product-binding sites; Binding of dsRNA to the bluetongue virus core surface; Bluetongue virus outer capsid proteins VP2 and VP5; Bluetongue virus non-structural proteins; Bluetongue virus particle structure and cell entry mechanisms; Chapter 7 Molecular epidemiology studies of bluetongue virus; Introduction; Variable and conserved genome segments; BTV incursions into Europe; Phylogenetic analyses of BTV core/non-structural proteins and identification of reassortants 327 $aConclusions/DiscussionChapter 8 Bluetongue in the Indian subcontinent; Introduction; Geographical distribution and seasonality; Clinical bluetongue in sheep; Serological prevalence of bluetongue in other animal species; Vectors; Bluetongue virus serotypes reported from Indian subcontinent; Diagnosis; Molecular epidemiology studies; Economic impact of bluetongue and control; Acknowledgments; Chapter 9 Current status of bluetongue virus in the Americas; Introduction; North America; Central America; South America; Virus-vector Interactions; Summary; Acknowledgments 327 $aChapter 10 Bluetongue viruses in Australasia and East Asia 330 $aThe third volume in the Institute of Animal Health (IAH) Biology of Animal Infections Series, Bluetongue discusses one of the most economically important diseases of domesticated livestock. Affecting primarily sheep particularly the improved mutton and wool breeds, it is now endemic in Africa, India, the Middle and Far East, Australia and the Americas, and over the last six years has caused a series of outbreaks throughout the Mediterranean region and central Europe. Bluetongue represent a paradigm not only for the other orbiviruses (such as African horse sickness virus, which sh 410 0$aBiology of animal infections. 606 $aBluetongue 606 $aBluetongue virus 606 $aBluetongue$xEpidemiology 606 $aAnimals as carriers of disease 606 $aCulicoides 606 $aCattle$xVirus diseases 606 $aSheep$xVirus diseases 615 0$aBluetongue. 615 0$aBluetongue virus. 615 0$aBluetongue$xEpidemiology. 615 0$aAnimals as carriers of disease. 615 0$aCulicoides. 615 0$aCattle$xVirus diseases. 615 0$aSheep$xVirus diseases. 676 $a636.089 676 $a636.089691 701 $aMertens$b Peter P. C$01352833 701 $aBaylis$b Matthew$01352834 701 $aMellor$b P. S$g(Philip S.)$01352835 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910698584903321 996 $aBluetongue$93204131 997 $aUNINA