LEADER 02872nam 2200469Ia 450 001 9910698434203321 005 20200520144314.0 010 $a1-282-03635-1 010 $a1-60327-329-8 010 $a9786612036354 035 $a(CKB)1000000000716746 035 $a(VLeBooks)9781603273299 035 $a(MiAaPQ)EBC428811 035 $a(EXLCZ)991000000000716746 100 $a20080512d2009 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aPost-traumatic stress disorder $ebasic science and clinical practice /$fedited by Priyattam J. Shiromani, Terence M. Keane, Joseph E. LeDoux 210 $aTotowa, N.J. $cHumana$dc2009 215 $a1 online resource (406 p.) 311 $a1-60327-328-X 311 $a1-62703-804-3 320 $aIncludes bibliographical references and index. 330 $a Post-traumatic stress disorder is a psychiatric illness that can occur in anyone who has experienced a life-threatening or violent event. The trauma can be due to war, terrorism, torture, natural disasters, violence, or rape. In PTSD the brain areas that are likely to be affected are the hippocampus (memory), amygdala (fear association), the prefrontal cortex (cognitive processing), and the ascending reticular activating system (arousal). The chemical of interest is norepinephrine, which is released during a stressful event and is part of the fight-or-flight response meant to mobilize the body to action.The objective of this title is to outline the neurobiology of post-traumatic stress disorder and provide treatment strategies for clinicians. The chapter material from this book has evolved from a seminar on PTSD held recently under the auspices of the VA Boston Healthcare System, Boston University Medical Center and Harvard Medical School.  We propose a book that will focus on the epidemiology, neurobiology, MRI studies, animal models, arousal and sleep issues, clinical trials, and treatment strategies for clinicians. Treatment will cover such topics as guidelines for treating posttraumatic stress disorder, PTSD and the use of mental health services, cognitive intervention therapy, and large scale clinical trials in PTSD. This collection will be a vital source of information to clinicians and neuroscientists. 606 $aPost-traumatic stress disorder 606 $aStress (Psychology) 615 0$aPost-traumatic stress disorder. 615 0$aStress (Psychology) 676 $a616.8521 701 $aKeane$b Terence Martin$01500282 701 $aLeDoux$b Joseph E$0296306 701 $aShiromani$b Priyattam J$01763262 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910698434203321 996 $aPost-traumatic stress disorder$94203622 997 $aUNINA