LEADER 04522nam 2200709Ia 450 001 9910450042803321 005 20210615022946.0 010 $a1-59734-456-7 010 $a1-282-75923-X 010 $a9786612759239 010 $a0-520-93026-6 024 7 $a10.1525/9780520930261 035 $a(CKB)1000000000000482 035 $a(EBL)223261 035 $a(OCoLC)475927489 035 $a(SSID)ssj0000100559 035 $a(PQKBManifestationID)11128306 035 $a(PQKBTitleCode)TC0000100559 035 $a(PQKBWorkID)10021075 035 $a(PQKB)10449725 035 $a(SSID)ssj0000356441 035 $a(PQKBManifestationID)12099684 035 $a(PQKBTitleCode)TC0000356441 035 $a(PQKBWorkID)10349620 035 $a(PQKB)11036367 035 $a(MiAaPQ)EBC223261 035 $a(OCoLC)51821986 035 $a(MdBmJHUP)muse31030 035 $a(DE-B1597)519684 035 $a(DE-B1597)9780520930261 035 $a(Au-PeEL)EBL223261 035 $a(CaPaEBR)ebr10051553 035 $a(CaONFJC)MIL275923 035 $a(EXLCZ)991000000000000482 100 $a20040503d2003 my 0 101 0 $aeng 135 $aurnn#---|u||u 181 $ctxt 182 $cc 183 $acr 200 10$aAhead of the curve$b[electronic resource] $eDavid Baltimore's life in science /$fShane Crotty 210 $aBerkeley, Calif. $cUniversity of California Press$dc2003 215 $a1 online resource (302 p.) 300 $aDescription based upon print version of record. 311 0 $a0-520-22557-0 311 0 $a0-520-23904-0 320 $aIncludes bibliographical references and index. 327 $tFront matter --$tCONTENTS --$tPROLOGUE --$tONE. GREAT NECK, LONG ISLAND --$tTWO. SWARTHMORE --$tTHREE. APPRENTICESHIPS --$tFOUR. SALK INSTITUTE --$tFIVE. MIT --$tSIX. RECOMBINANT DNA --$tSEVEN. NOBELGOLD --$tPOLIOVIRUS: AN INTERLUDE --$tEIGHT. WHITEHEAD INSTITUTE --$tNINE. ROCKEFELLER --$tTEN. HOMECOMING --$tELEVEN. CALTECH --$tACKNOWLEDGMENTS --$tNOTES --$tINDEX 330 $aShane Crotty's biography of David Baltimore details the life and work of one of the most brilliant, powerful, and controversial scientists of our time. Although only in his early sixties, Baltimore has made major discoveries in molecular biology, established the prestigious Whitehead Institute at MIT, been president of Rockefeller University, won the Nobel Prize, and been vilified by detractors in one of the most scandalous and protracted investigations of scientific fraud ever. He is now president of Caltech and a leader in the search for an AIDS vaccine. Crotty not only tells the compelling story of this larger-than-life figure, he also treats the reader to a lucid account of the amazing revolution that has occurred in biology during the past forty years. Basing his narrative on many personal interviews, Crotty recounts the milestones of Baltimore's career: completing his Ph.D. at Rockefeller University in eighteen months, participating in the anti-Vietnam War movement, winning a Nobel Prize at age thirty-seven for the codiscovery of reverse transcriptase, and co-organizing the recombinant DNA/genetic engineering moratorium. Along the way, readers learn what viruses are and what they do, what cancer is and how it happens, the complexities of the AIDS problem, how genetic engineering works, and why making a vaccine is a complicated process. And, as Crotty considers Baltimore's public life, he retells the famous scientific fraud saga and Baltimore's vindication after a decade of character assassination. Crotty possesses the alchemical skill of converting technical scientific history into entertaining prose as he conveys Baltimore's huge ambitions, intensity, scientific genius, attitude toward science and politics, and Baltimore's own view about what happened in the "Baltimore Affair." Ahead of the Curve shows why with his complex personality, keen involvement in public issues, and wide-ranging interests David Baltimore has not only shaped the face of American science as we know it today, but has also become a presence in our culture. 606 $aMolecular biologists$zUnited States$vBiography 608 $aElectronic books. 615 0$aMolecular biologists 676 $a572.8/092 B 686 $aTB 3120$2rvk 700 $aCrotty$b Shane$f1974-$01031417 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910450042803321 996 $aAhead of the curve$92448787 997 $aUNINA LEADER 01850nam 2200541Ia 450 001 9910698070203321 005 20090210093323.0 035 $a(CKB)5470000002394299 035 $a(OCoLC)302340674 035 $a(EXLCZ)995470000002394299 100 $a20090210d1989 ua 0 101 0 $aeng 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aERBE/NOAA-9 observations for the FIRE/SRB Wisconsin experiment region from October 14 through October 31, 1986$b[electronic resource] /$fCharles H. Whitlock, Lawrence H. Hoffman, and Robert F. Arduini 210 1$aHampton, Va. :$cNational Aeronautics and Space Administration, Langley Research Center,$d[1989] 215 $ai, 31 pages $cdigital, PDF file 225 1 $aNASA technical memorandum ;$v101627 300 $aTitle from title screen (viewed Feb. 9, 2009) 300 $a"July 1989." 320 $aIncludes bibliographical references (page 5). 606 $aClouds$zWisconsin 606 $aTerrestrial radiation$zWisconsin 606 $aEarth radiation budget experiment$2nasat 606 $aPixels$2nasat 606 $aPoint spread functions$2nasat 606 $aPosition (location)$2nasat 606 $aRadiance$2nasat 606 $aWisconsin$2nasat 615 0$aClouds 615 0$aTerrestrial radiation 615 7$aEarth radiation budget experiment. 615 7$aPixels. 615 7$aPoint spread functions. 615 7$aPosition (location) 615 7$aRadiance. 615 7$aWisconsin. 700 $aWhitlock$b Charles H$01406991 701 $aHoffman$b Lawrence H$01417085 701 $aArduini$b R. F$01417086 712 02$aLangley Research Center. 801 0$bGPO 801 1$bGPO 906 $aBOOK 912 $a9910698070203321 996 $aERBE$93524384 997 $aUNINA LEADER 05596nam 22006974a 450 001 9910830759303321 005 20230721030018.0 010 $a1-119-20926-9 010 $a1-280-85604-1 010 $a9786610856046 010 $a0-470-51272-5 035 $a(CKB)1000000000357148 035 $a(EBL)292595 035 $a(OCoLC)437178643 035 $a(SSID)ssj0000252714 035 $a(PQKBManifestationID)12040235 035 $a(PQKBTitleCode)TC0000252714 035 $a(PQKBWorkID)10180667 035 $a(PQKB)10674416 035 $a(MiAaPQ)EBC292595 035 $a(EXLCZ)991000000000357148 100 $a20070312d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aStructured finance$b[electronic resource] $ethe object oriented approach /$fUmberto Cherubini, Giovanni Della Lunga 210 $aChichester, England ;$aHoboken, NJ $cJohn Wiley & Sons$dc2007 215 $a1 online resource (300 p.) 225 1 $aWiley finance series 300 $aDescription based upon print version of record. 311 $a0-470-02638-3 320 $aIncludes bibliographical references and index. 327 $aStructured Finance; Contents; 1 Structured Finance: A Primer; 1.1 Introduction; 1.2 Arbitrage-free valuation and replicating portfolios; 1.3 Replicating portfolios for derivatives; 1.3.1 Linear derivatives; 1.3.2 Nonlinear derivatives; 1.4 No-arbitrage and pricing; 1.4.1 Univariate claims; 1.4.2 Multivariate claims; 1.5 The structuring process; 1.5.1 The basic objects; 1.5.2 Risk factors, moments and dimensions; 1.5.3 Risk management; 1.6 A tale of two bonds; 1.6.1 Contingent coupons and repayment plans; 1.6.2 Exposure to the risky asset; 1.6.3 Exposure to volatility; 1.6.4 Hedging 327 $a1.7 Structured finance and object-oriented programmingReferences and further reading; 2 Object-Oriented Programming; 2.1 Introduction; 2.2 What is OOP (object-oriented programming)?; 2.3 Analysis and design; 2.3.1 A simple example; 2.4 Modelling; 2.4.1 The Unified Modelling Language (UML); 2.4.2 An object-oriented programming language: Java; 2.5 Main ideas about OOP; 2.5.1 Abstraction; 2.5.2 Classes; 2.5.3 Attributes and operations: the Encapsulation principle; 2.5.4 Responsibilities; 2.5.5 Inheritance; 2.5.6 Abstract classes; 2.5.7 Associations; 2.5.8 Message exchanging; 2.5.9 Collections 327 $a2.5.10 PolymorphismReferences and further reading; 3 Volatility and Correlation; 3.1 Introduction; 3.2 Volatility and correlation: models and measures; 3.2.1 Implied information; 3.2.2 Parametric models; 3.2.3 Realized (cross)moments; 3.3 Implied probability; 3.4 Volatility measures; 3.4.1 Implied volatility; 3.4.2 Parametric volatility models; 3.4.3 Realized volatility; 3.5 Implied correlation; 3.5.1 Forex markets implied correlation; 3.5.2 Equity "average" implied correlation; 3.5.3 Credit implied correlation; 3.6 Historical correlation; 3.6.1 Multivariate GARCH 327 $a3.6.2 Dynamic correlation model3.7 Copula functions; 3.7.1 Copula functions: the basics; 3.7.2 Copula functions: examples; 3.7.3 Copulas and survival copulas; 3.7.4 Copula dualities; 3.8 Conditional probabilities; 3.9 Non-parametric measures; 3.10 Tail dependence; 3.11 Correlation asymmetry; 3.11.1 Correlation asymmetry: finance; 3.11.2 Correlation asymmetry: econometrics; 3.12 Non-exchangeable copulas; 3.13 Estimation issues; 3.14 Le?vy processes; References and further reading; 4 Cash Flow Design; 4.1 Introduction; 4.2 Types of bonds; 4.2.1 Floaters and reverse floaters 327 $a4.2.2 Convertible bonds4.2.3 Equity-linked notes; 4.2.4 Inflation-linked bonds; 4.2.5 Asset-backed securities; 4.3 Time and scheduler issues; 4.3.1 Payment date conventions; 4.3.2 Day count conventions and accrual factors; 4.4 JScheduler; 4.4.1 Date handling in Java; 4.4.2 Data models; 4.4.3 Design patterns; 4.4.4 The Factory Method pattern; 4.5 Cash flow generator design; 4.5.1 UML's activity diagram; 4.5.2 An important guideline to the data model for derivatives: FpML; 4.5.3 UML's sequence diagram; 4.6 The cleg class; References and further reading; 5 Convertible Bonds; 5.1 Introduction 327 $a5.2 Object-oriented structuring process 330 $aStructured Finance: The Object Orientated Approach is aimed at both the finance and IT professionals involved in the structured finance business with the intention of sharing common concepts and language within the industry. The financial community (structurers, pricers and risk managers) view structured products as collections of objects under the so-called replicating portfolio paradigm. The IT community use object oriented programming (OOP) techniques to improve the software updating and maintenance process. For them structured products are collections of objects as well. Despite use 410 0$aWiley finance series. 606 $aStructured notes (Securities) 606 $aDerivative securities 606 $aInvestment analysis$xMathematical models 606 $aFinancial engineering 615 0$aStructured notes (Securities) 615 0$aDerivative securities. 615 0$aInvestment analysis$xMathematical models. 615 0$aFinancial engineering. 676 $a332.0285117 676 $a332.602855117 700 $aCherubini$b Umberto$0118857 701 $aDella Lunga$b Giovanni$0121168 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830759303321 996 $aStructured finance$93934105 997 $aUNINA