LEADER 00900cam0 2200265 450 001 E600200062241 005 20160427095822.0 100 $a20100325d1984 |||||ita|0103 ba 101 $aeng 102 $aZA 200 1 $a<>fate of the Institutional System$fPeter Stein 210 $a[S.l$cs.e.$d1984?] 215 $ap. 218-227$d22 cm 300 $a(mm) 300 $aEstr. da: Huldigingsbundel Paul van Warmelo, Pretoria, 1984 700 1$aStein$b, Peter$3AF00009297$4070$043339 801 0$aIT$bUNISOB$c20160427$gRICA 850 $aUNISOB 852 $aUNISOB$jFondo|Casavola|Opusc$m148645 912 $aE600200062241 940 $aM 102 Monografia moderna SBN 941 $aM 957 $aFondo|Casavola|Opusc$b000405$gSi$d148645$hCasavola$rdono$1menle$2UNISOB$3UNISOB$420100325101054.0$520160427095822.0$6petrellap 996 $aFate of the Institutional System$91705199 997 $aUNISOB LEADER 01676nam 2200469Ia 450 001 9910696921203321 005 20230902161735.0 035 $a(CKB)5470000002383683 035 $a(OCoLC)640123001 035 $a(EXLCZ)995470000002383683 100 $a20100611d2009 ua 0 101 0 $aeng 135 $aurmn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aSimulating bone loss in microgravity using mathematical formulations of bone remodeling$b[electronic resource] /$fJames A. Pennline 210 1$aCleveland, Ohio :$cNational Aeronautics and Space Administration, Glenn Research Center,$d[2009] 215 $a1 online resource (21 pages) $cillustrations 225 1 $aNASA TM- ;$v2009-215824 300 $aTitle from title screen (viewed on June 11, 2010). 300 $a"November 2009." 320 $aIncludes bibliographical references (pages 14-15). 410 0$aNASA technical memorandum ;$v2009-215824. 606 $aBone demineralization$2nasat 606 $aMathematical models$2nasat 606 $aMusculoskeletal system$2nasat 606 $aBiochemistry$2nasat 606 $aMicrogravity$2nasat 615 7$aBone demineralization. 615 7$aMathematical models. 615 7$aMusculoskeletal system. 615 7$aBiochemistry. 615 7$aMicrogravity. 700 $aPennline$b James A$01408297 712 02$aNASA Glenn Research Center. 801 0$bGPO 801 1$bGPO 906 $aBOOK 912 $a9910696921203321 996 $aSimulating bone loss in microgravity using mathematical formulations of bone remodeling$93548503 997 $aUNINA LEADER 03684nam 2200601 a 450 001 9910974461903321 005 20251017110115.0 010 $a0-309-21107-7 010 $a1-283-21343-5 010 $a9786613213433 010 $a0-309-21105-0 035 $a(CKB)2550000000042938 035 $a(EBL)3378803 035 $a(MiAaPQ)EBC3378803 035 $a(Au-PeEL)EBL3378803 035 $a(CaPaEBR)ebr10488624 035 $a(CaONFJC)MIL321343 035 $a(OCoLC)923283637 035 $a(DNLM)1568301 035 $a(EXLCZ)992550000000042938 100 $a20110827d2011 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGenerating evidence for genomic diagnostic test development $eworkshop Summary /$fTheresa Wizemann and Adam C. Berger, rapporteurs ; Roundtable on translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies 205 $a1st ed. 210 $aWashington, D.C. $cNational Academies Press$d2011 215 $a1 online resource (100 p.) 300 $aDescription based upon print version of record. 311 08$a0-309-21104-2 320 $aIncludes bibliographical references. 327 $a""Front Matter""; ""Reviewers""; ""Acknowledgments""; ""Contents""; ""Tables, Figures, and Boxes""; ""Abbreviations and Acronyms""; ""1 Introduction""; ""2 Stakeholder Perspectives on Evidence""; ""3 Approaches to Evidence Generation""; ""4 Overcoming Barriers for Evidence Generation""; ""5 Considerations Moving Forward""; ""6 Final Remarks""; ""References""; ""Appendix A: Workshop Agenda""; ""Appendix B: Speaker Biographical Sketches""; ""Appendix C: Registered Attendees"" 330 $a"Ten years after the sequencing of the human genome, scientists have developed genetic tests that can predict a person's response to certain drugs, estimate the risk of developing Alzheimer's disease, and make other predictions based on known links between genes and diseases. However, genetic tests have yet to become a routine part of medical care, in part because there is not enough evidence to show they help improve patients' health.The Institute of Medicine (IOM) held a workshop to explore how researchers can gather better evidence more efficiently on the clinical utility of genetic tests. Generating Evidence for Genomic Diagnostic Test Development compares the evidence that is required for decisions regarding clearance, use, and reimbursement, to the evidence that is currently generated. The report also addresses innovative and efficient ways to generate high-quality evidence, as well as barriers to generating this evidence. Generating Evidence for Genomic Diagnostic Test Development contains information that will be of great value to regulators and policymakers, payers, health-care providers, researchers, funders, and evidence-based review groups."--Publisher's description. 606 $aGenomics 606 $aDiagnosis 606 $aGene mapping 615 0$aGenomics. 615 0$aDiagnosis. 615 0$aGene mapping. 676 $a616.0420027 701 $aWizemann$b Theresa M$0890630 701 $aBerger$b Adam C$01120088 712 02$aInstitute of Medicine (U.S.).$bRoundtable on Translating Genomic-Based Research for Health. 712 02$aInstitute of Medicine (U.S.).$bBoard on Health Sciences Policy. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910974461903321 996 $aGenerating evidence for genomic diagnostic test development$94447104 997 $aUNINA