LEADER 04495nam 2200673Ia 450 001 9910788549103321 005 20230116114421.0 010 $a3-11-091111-6 024 7 $a10.1515/9783110911114 035 $a(CKB)3360000000338322 035 $a(EBL)913095 035 $a(OCoLC)850178378 035 $a(SSID)ssj0000559733 035 $a(PQKBManifestationID)11955537 035 $a(PQKBTitleCode)TC0000559733 035 $a(PQKBWorkID)10567475 035 $a(PQKB)11034876 035 $a(MiAaPQ)EBC913095 035 $a(WaSeSS)Ind00014126 035 $a(DE-B1597)56794 035 $a(OCoLC)979763138 035 $a(DE-B1597)9783110911114 035 $a(Au-PeEL)EBL913095 035 $a(CaPaEBR)ebr10597471 035 $a(EXLCZ)993360000000338322 100 $a20060330d2006 uy 0 101 0 $aeng 135 $aurnn#---|u||u 181 $ctxt 182 $cc 183 $acr 200 00$aEthnopragmatics$b[electronic resource] $eunderstanding discourse in cultural context /$fedited by Cliff Goddard 210 $aBerlin ;$aNew York $cMouton de Gruyter$dc2006 215 $a1 online resource (288 p.) 225 0 $aApplications of cognitive linguistics,$x1861-4078 ;$v3 300 $aDescription based upon print version of record. 311 0 $a3-11-018874-0 320 $aIncludes bibliographical references and index. 327 $tFront matter --$t1. Ethnopragmatics: a new paradigm /$rGoddard, Cliff --$t2. Anglo scripts against "putting pressure" on other people and their linguistic manifestations /$rWierzbicka, Anna --$t3. "Lift your game Martina!": deadpan jocular irony and the ethnopragmatics of Australian English /$rGoddard, Cliff --$t4. Social hierarchy in the "speech culture" of Singapore /$rWong, Jock Onn --$t5. Why the "inscrutable" Chinese face? Emotionality and facial expression in Chinese /$rYe, Zhengdao --$t6. Cultural scripts: glimpses into the Japanese emotion world /$rHasada, Rie --$t7. The communicative realisation of confianza and calor humano in Colombian Spanish /$rTravis, Catherine E. --$t8. "When I die, don't cry": the ethnopragmatics of "gratitude" in West African languages /$rAmeka, Felix K. --$tAuthor index --$tGeneral index 330 $aThe studies in this volume show how speech practices can be understood from a culture-internal perspective, in terms of values, norms and beliefs of the speech communities concerned. Focusing on examples from many different cultural locations, the contributing authors ask not only: 'What is distinctive about these particular ways of speaking?', but also: 'Why - from their own point of view - do the people concerned speak in these particular ways? What sense does it make to them?'. The ethnopragmatic approach stands in opposition to the culture-external universalist pragmatics represented by neo-Gricean pragmatics and politeness theory. Using "cultural scripts" and semantic explications - techniques developed over 20 years work in cross-cultural semantics by Anna Wierzbicka and colleagues - the authors examine a wide range of phenomena, including: speech acts, terms of address, phraseological patterns, jocular irony, facial expressions, interactional routines, discourse particles, expressive derivation, and emotionality. The authors and languages are: Anna Wierzbicka (English), Cliff Goddard (Australian English), Jock Wong (Singapore English), Zhengdao Ye (Chinese), Catherine Travis (Colombian Spanish), Rie Hasada (Japanese) and Felix Ameka (Ewe). Taken together, these studies demonstrate both the profound "cultural shaping" of speech practices, and the power and subtlety of new methods and techniques of a semantically grounded ethnopragmatics. The book will appeal not only to linguists and anthropologists, but to all scholars and students with an interest in language, communication and culture. 410 0$aApplications of Cognitive Linguistics [ACL] 606 $aPragmatics$xSocial aspects 606 $aLanguage and culture 606 $aSemantics$xSocial aspects 610 $aPragmatics. 610 $aintercultural studies. 615 0$aPragmatics$xSocial aspects. 615 0$aLanguage and culture. 615 0$aSemantics$xSocial aspects. 676 $a306.44 686 $aES 135$2rvk 701 $aGoddard$b Cliff$0174092 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910788549103321 996 $aEthnopragmatics$93676374 997 $aUNINA LEADER 05497nam 2200673 450 001 9910787406103321 005 20200520144314.0 010 $a1-118-90141-X 010 $a1-118-90138-X 035 $a(CKB)3710000000361281 035 $a(EBL)1895726 035 $a(SSID)ssj0001438522 035 $a(PQKBManifestationID)11916980 035 $a(PQKBTitleCode)TC0001438522 035 $a(PQKBWorkID)11377128 035 $a(PQKB)10697108 035 $a(MiAaPQ)EBC1895726 035 $a(Au-PeEL)EBL1895726 035 $a(CaPaEBR)ebr11027518 035 $a(CaONFJC)MIL770056 035 $a(OCoLC)881518557 035 $a(PPN)189834587 035 $a(EXLCZ)993710000000361281 100 $a20150312h20152015 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aPharmaceutical amorphous solid dispersions /$fedited by Ann Newman, Seventh Street Development Group Lafayette, Indiana, USA ; contributors, Patrick Augustijns [and forty seven others] 210 1$aHoboken, New Jersey :$cWiley,$d2015. 210 4$dİ2015 215 $a1 online resource (1218 p.) 300 $aDescription based upon print version of record. 311 $a1-118-45520-7 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aCover; Title Page; Copyright; Dedication; Preface; Contributors; 1.1 Introduction; 1.2 Formation of the Amorphous State and the Glass Transition Temperature; 1.3 Structure of Amorphous Solids; 1.4 Molecular Mobility in Amorphous Solids; 1.5 Solid-State Crystallization from the Amorphous State; 1.6 Supersaturation of API in Aqueous Media from the Amorphous State; 1.7 Mixtures of Amorphous Solids; 1.8 Formation and Properties of Amorphous Solid Dispersions; 1.9 Solid-State Crystallization from Amorphous Dispersions; 1.10 Dissolution and Supersaturation of API from Amorphous Solid Dispersions 327 $a1.11 Pharmaceutical Development of Amorphous Solid DispersionsReferences; Chapter 1: Introduction to Amorphous Solid Dispersions; 2.1 Polymers Commonly Used in Amorphous Solid Dispersions; 2.2 Surfactants Commonly Used in Solid Dispersions; 2.3 Synergies between Surfactants and Polymers in Solid Dispersion Systems; 2.4 Physical Properties of Materials and Considerations in Designing Solid Dispersions; References; Chapter 2: Polymers and Surfactants; 3.1 Introduction; 3.2 Amorphous Dispersion Screening; 3.3 Amorphous Solid Dispersion Selection; 3.4 Case Study; 3.5 Conclusions; References 327 $aChapter 3: Amorphous Solid Dispersion Screening4.1 Introduction; 4.2 Thermal Analysis Methods; 4.3 Dielectric Relaxation Methods; 4.4 Moisture Sorption Methods; 4.5 Vibrational Spectroscopy and Microspectroscopy; 4.6 Solid-State NMR Spectroscopy; 4.7 Other Molecular Spectroscopic Methods; 4.8 X-Ray Diffractometry; 4.9 Microscopic and Surface Analysis Methods; 4.10 Other Emerging Analytical Methods; 4.11 Computational Models; 4.12 Conclusions; Acknowledgments; References; Chapter 4: Solid-State Characterization of Amorphous Dispersions; 5.1 Introduction 327 $a5.2 Theory of Crystallization in the Solid State5.3 Factors Impacting the Crystallization Tendency of Active Pharmaceutical Compounds; 5.4 Role of Additives in Modifying Solid-State Crystallization; 5.5 Assessment of Physical Stability; 5.6 Crystallization in Aqueous Environments; 5.7 Summary and Outlook; References; Chapter 5: Physical Stability and Crystallization Inhibition; 6.1 Solubility and Dissolution: An Overview; 6.2 Differences Between Crystalline API, Amorphous Materials, and Amorphous Dispersions as it Pertains to Solubility and Dissolution 327 $a6.3 The Relationship of Polymer Properties with Solubility, Dissolution, and Supersaturation6.4 Solubility and Dissolution Factors to Consider for Dispersions; 6.5 Solubility and Dissolution Measurements for Amorphous Dispersions: Summary, Conclusions, and Recommendations; Acknowledgments; References; Chapter 6: Solubility and Dissolution Considerations for Amorphous Solid Dispersions; 7.1 Introduction: Translational Drug Development; 7.2 Translational Development at the Discovery Stage; 7.3 Translational Development After Discovery; 7.4 Conclusions; References 327 $aChapter 7: Translational Development of Amorphous Dispersions 330 $aProviding a roadmap from early to late stages of drug development, this book overviews amorphous solid dispersion technology - a leading platform to deliver poorly water soluble drugs, a major hurdle in today's pharmaceutical industry. Helps readers understand amorphous solid dispersions and apply techniques to particular pharmaceutical systems Covers physical and chemical properties, screening, scale-up, formulation, drug product manufacture, intellectual property, and regulatory considerations Has an appendix with structure and property information for polymers commonly used in drug developm 606 $aPharmaceutical technology 606 $aAbsorption 606 $aSolubility 615 0$aPharmaceutical technology. 615 0$aAbsorption. 615 0$aSolubility. 676 $a615.7 702 $aNewman$b Ann$c(Pharmaceutical scientist), 702 $aAugustijns$b Patrick 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910787406103321 996 $aPharmaceutical amorphous solid dispersions$93760534 997 $aUNINA LEADER 01873nam 2200373z- 450 001 9910694017403321 005 20120322082312.0 035 $a(CKB)5860000000032653 035 $a(BIP)022167604 035 $a(EXLCZ)995860000000032653 100 $a20220406c2006uuuu -u- - 101 0 $aeng 200 10$aRequesting the President of the United States and directing the Secretary of State to provide to the House of Representatives certain documents in their possession relating to the White House Iraq Group $emarkup before the Committee on International Relations, House of Representatives, One Hundred Ninth Congress, first session, on H. 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