LEADER 01866nam 2200373 450 001 9910688581803321 005 20230623125816.0 035 $a(CKB)5400000000040666 035 $a(NjHacI)995400000000040666 035 $a(EXLCZ)995400000000040666 100 $a20230623d2020 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aLupus $enew advances and challenges /$fedited by Sophia Lionaki 210 1$aLondon, England :$cIntechOpen,$d2020. 215 $a1 online resource (138 pages) 311 $a1-83880-184-7 330 $aSystemic lupus erythematosus, the prototype of an autoimmune disorder, may affect several organs and may run a chronic course between relapse and remission. This book covers important aspects of the disease, including epidemiology, pathophysiology, and neuropsychiatric manifestations, including basic science and clinical features and management. In affected patients, the fundamental problem of fertility is reassessed including the risk of the disease, the possibility of fetal loss, the safety of drugs during pregnancy, and the current diagnostic and suggested therapeutic strategies of reproductive medicine. Finally, the issue of pathogenesis is revisited with a thorough description of animal models in relation to physiology and potential novel therapies. 517 $aLupus 606 $aSystemic lupus erythematosus$vPopular works 606 $aSystemic lupus erythematosus$xAlternative treatment 615 0$aSystemic lupus erythematosus 615 0$aSystemic lupus erythematosus$xAlternative treatment. 676 $a616.77 702 $aLionaki$b Sophia 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910688581803321 996 $aLupus$91927242 997 $aUNINA