LEADER 02050nam 2200445z- 450 001 9910688571803321 005 20210211 035 $a(CKB)4100000002484712 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/53226 035 $a(oapen)doab53226 035 $a(EXLCZ)994100000002484712 100 $a20202102d2017 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMetabolic Control of Brain Homeostasis 210 $cFrontiers Media SA$d2017 215 $a1 online resource (204 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-286-7 330 $aBrain function is under metabolic control, which in turn determines the equilibrium of homeostatic systems that affect neuronal and glial networks on the molecular, cellular, and systems levels. The collection of articles ranges from molecules and mechanisms involved in regulating homeostasis and neuronal excitability to therapeutic mechanisms tailored to restore homeostatic function. It also features neurological diseases and novel treatment approaches that are based on metabolic and homeostatic interventions. Together, the collection of articles outlines novel strategies to restore brain function in neurology and highlights limitations of conventional pharmacological approaches. We suggest that restoration of molecular and biochemical networks could lead to a new era of therapeutic opportunities. 606 $aNeurosciences$2bicssc 610 $aAlzheimer's disease 610 $aautism 610 $abrain cancer 610 $aepilepsy 610 $aketogenic diet 610 $ametabolism 610 $aradiation 610 $aRNA editing 615 7$aNeurosciences 700 $aSusan A. Masino$4auth$01351848 702 $aDetlev Boison$4auth 702 $aJochen C. Meier$4auth 906 $aBOOK 912 $a9910688571803321 996 $aMetabolic Control of Brain Homeostasis$93136479 997 $aUNINA