LEADER 02193nam 2200349 450 001 9910688489403321 005 20230628213134.0 035 $a(CKB)5400000000043911 035 $a(NjHacI)995400000000043911 035 $a(EXLCZ)995400000000043911 100 $a20230628d2020 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMacrophage Activation $ebiology and disease /$fKhalid Hussain Bhat 210 1$aLondon :$cIntechOpen,$d2020. 215 $a1 online resource (132 pages) 311 $a1-78985-574-8 330 $aMacrophages are the sentinels of the immune system whose role has evolved beyond providing aseptic conditions to homeostasis, immune regulation, development, and behaviour. These cells have varied ontogenetic origins which reflects in their phenotypic and functional heterogeneity. Macrophage functions are fine-tuned by exogenous and endogenous signals and once tweaked, the information is included in their genetic makeup, albeit not indefinitely. Subversion of the macrophage functions is the hallmark of many pathogenic organisms and modulation of macrophage activity is pivotal to many therapeutic strategies. Fascinating and rapid developments in this field have necessitated the maintenance of currency of knowledge. This book provides a current account of information on varied topics in macrophage biology. Literature surveys have been presented in a captivating and lucid language. The contributing authors have also provided brief accounts of their own research. Every chapter provides a future perspective of what more could be achieved in the context of the current knowledge. The book will be of interest to students and researchers in microbiology, immunobiology, translational research, pathology, and related fields. 517 $aMacrophage Activation 606 $aMacrophages 615 0$aMacrophages. 676 $a616.07995 700 $aBhat$b Khalid Hussain$01368490 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910688489403321 996 $aMacrophage Activation$93394308 997 $aUNINA