LEADER 01913nam  2200361   450 
001 9910688461603321
005 20230628094726.0
035   $a(CKB)5400000000043316
035   $a(NjHacI)995400000000043316
035   $a(EXLCZ)995400000000043316
100   $a20230628d2020      uy             0
101 0 $aeng
135   $aur|||||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aMitochondria and Brain Disorders /$fedited by Stavros J. Baloyannis
210  1$aLondon, England :$cIntechOpen,$d2020.
215   $a1 online resource (124 pages)
311   $a1-78985-653-1 
330   $aThe mitochondrion is a unique and ubiquitous organelle that contains its own genome, encoding essential proteins that are major components of the respiratory chain and energy production system. Mitochondria play a dominant role in the life and function of eukaryotic cells including neurons and glia, as their survival and activity depend upon mitochondrial energy production and supply. Besides energy production, mitochondria also play a vital role in calcium homeostasis and may induce apoptosis by excitotoxicity. Mitochondrial dysfunction is related to common neurological diseases, such as Parkinson's disease, Alzheimer's disease, Friedreich's ataxia, Huntington's disease, and Multiple Sclerosis. An efficient treatment of mitochondrial dysfunction would open new horizons in the therapeutic perspectives of a substantial number of inflammatory and degenerative neurological disorders.
606   $aMitochondria
606   $aBrain$xDiseases$xEtiology
615  0$aMitochondria.
615  0$aBrain$xDiseases$xEtiology.
676   $a571.657
702   $aBaloyannis$b Stavros J.
801  0$bNjHacI
801  1$bNjHacl
906   $aBOOK
912   $a9910688461603321
996   $aMitochondria and Brain Disorders$91944353
997   $aUNINA