LEADER 01938nam 2200337 450 001 9910688461303321 005 20230630041156.0 035 $a(CKB)5400000000044762 035 $a(NjHacI)995400000000044762 035 $a(EXLCZ)995400000000044762 100 $a20230630d2020 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aQuinazolinone and Quinazoline Derivatives /$fAli Gamal Al-kaf, editor 210 1$aLondon :$cIntechOpen,$d2020. 215 $a1 online resource (xii, 113 pages) 311 $a1-83880-053-0 330 $aOne of the problems with modern public health is target searching for new highly effective medicinal preparations. Among those medicinal preparations are the natural and synthetic origins of quinazolinone-4 derivatives. Quinazolinone derivatives are reported to be physiologically and pharmacologically active. They also exhibit a wide range of activities such as anticonvulsant, antiinflammatory, antifungal, antimalarial, and sedative properties. Some of these compounds are identified as drugs used as diuretics, vasodilators, and antihypertensive agents. Moreover, sulfonamide derivatives have been widely used as bacteriostatic agents. Prompted by the above-mentioned facts and in conjunction with our ongoing program on the utility of readily obtainable starting material for the synthesis of heterocyclic systems of biological interest, we have decided to synthesize a series of quinazolinone derivatives having sulfonamide moiety with a potentially wide spectrum of biological responses. 606 $aCyclic compounds 615 0$aCyclic compounds. 676 $a547.6 702 $aAl-kaf$b Ali Gamal 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910688461303321 996 $aQuinazolinone and Quinazoline Derivatives$91915736 997 $aUNINA