LEADER 01698nam 2200349 450 001 9910688456203321 005 20230630044620.0 035 $a(CKB)5400000000044771 035 $a(NjHacI)995400000000044771 035 $a(EXLCZ)995400000000044771 100 $a20230630d2021 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aAdvances in Precision Medicine Oncology /$fHilal Arnouk, Bassam Hassan, editor 210 1$aLondon :$cIntechOpen,$d2021. 215 $a1 online resource (260 pages) 311 $a1-83968-869-6 330 $aRecent advances in precision medicine and immuno-oncology have led to highly specific and efficacious cancer therapies such as monoclonal antibodies and immune checkpoint inhibitors (ICIs). This book provides an up-to-date overview of advances in the field of immuno-oncology. Chapters cover such topics as ICIs and how they mount a robust immune response against cancer cells as well as the response of ICIs to treatment predictive biomarkers and their potential immune-related adverse events (irAEs). Additionally, the book includes a comprehensive review of the powerful FDA-approved therapeutic agent doxorubicin, highlighting the molecular mechanisms behind doxorubicin's drug resistance and critical side effects. 606 $aCancer$xTreatment 615 0$aCancer$xTreatment. 676 $a616.99406 702 $aHassan$b Bassam 702 $aArnouk$b Hilal 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910688456203321 996 $aAdvances in Precision Medicine Oncology$92828415 997 $aUNINA