LEADER 02614nam 2200373 450 001 9910688443903321 005 20230623215655.0 035 $a(CKB)5400000000043032 035 $a(NjHacI)995400000000043032 035 $a(EXLCZ)995400000000043032 100 $a20230623d2020 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aGrowth disorders and acromegaly /$fAhmed R. G., Ahmet Uc?ar, editor 210 1$aLondon :$cIntechOpen,$d[2020] 210 4$dİ2020 215 $a1 online resource 311 $a1-83880-585-0 327 $a1. Introductory Chapter: Growth Disorders -- 2. Growth Hormone Deficiency: Is It Just a Problem of Growth Impairment? Part I -- 3. Growth Hormone Deficiency: Is It Just a Problem of Growth Impairment? Part II -- 4. Fetal Growth Restriction -- 5. The Role of the Human Growth Hormone Gene Family in Pregnancy -- 6. Growth Hormone and Insulin-like Growth Factor-I: Novel Insights into the Male Reproductive Health -- 7. Pegvisomant in Acromegaly and Gigantism -- 8. Colorectal Neoplasm in Acromegaly: Epidemiology and Underlying Mechanisms -- 9. The Surgical Management of Acromegaly. 330 $aThe first two years of life represent a transition period when growth changes from predominantly growth hormone (GH) independent to GH dependent. This book, Growth Disorders and Acromegaly, includes two parts. The first part consists of five chapters that illustrate the nature, causes, types, signs, and symptoms of GH deficiency (GHD) and fetal growth restriction. It describes the impact of GH and its deficiency on different biological systems in children and adults. Also, this book assesses the role of human GH (hGH) and insulin-growth factor1 (IGF-1) gene families during pregnancy. This book offers several novel insights of GH in male reproductive health. The second part consists of three chapters that show the pegvisomant, colorectal neoplasms in acromegaly, epidemiology and underlying mechanisms, and the surgical managements of acromegaly. Finally, this book will be of interest to scientists, embryologists, neuroendocrinologists, neurotoxicologists, and physicians who follow recent developments in the field of growth disorders. 606 $aGrowth disorders 615 0$aGrowth disorders. 676 $a616.4042 702 $aUc?ar$b Ahmet 702 $aR. G. Ahmed 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910688443903321 996 $aGrowth Disorders and Acromegaly$92263326 997 $aUNINA