LEADER 01678nam 2200397 450 001 9910688378403321 005 20230626120442.0 035 $a(CKB)5580000000514407 035 $a(NjHacI)995580000000514407 035 $a(EXLCZ)995580000000514407 100 $a20230626d2022 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aIron metabolism $ea double-edged sword /$fedited by Marwa Zakaria, Tamer Hassan 210 1$aLondon, England :$cIntechOpen,$d2022. 215 $a1 online resource (162 pages) 225 1 $aBiochemistry ;$v37 311 $a1-83962-999-1 330 $aIron is an essential element for numerous fundamental biologic processes. Iron-containing proteins are required for vital cellular and organismal functions including oxygen transport, mitochondrial respiration, intermediary and xenobiotic metabolism, nucleic acid replication and repair, host defense, and cell signaling. However, excess iron is toxic. This book provides a comprehensive overview of the essential role of iron in biology, the regulation of systemic and cellular iron homeostasis, and how imbalances in iron homeostasis contribute to disease. 410 0$aBiochemistry ;$v37. 606 $aIron$xMetabolism 606 $aIron$xPhysiological effect 615 0$aIron$xMetabolism. 615 0$aIron$xPhysiological effect. 676 $a612.3924 702 $aZakaria$b Marwa 702 $aHassan$b Tamer 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910688378403321 996 $aIron Metabolism$9834677 997 $aUNINA