LEADER 04231oam 2200625 450 001 9910688342303321 005 20230621140415.0 010 $a9782889197644$b(ebook) 035 $a(CKB)3710000000631140 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/56386 035 $a(EXLCZ)993710000000631140 100 $a20191103h20162016 fy 0 101 0 $aeng 135 $aur||#|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPlasticity in multiple sclerosis $efrom molecular to system level, from adaptation to maladaptation /$fedited by Daniel Zeller and Maria Assunta Rocca 210 $cFrontiers Media SA$d2016 210 1$a[Lausanne, Switzerland] :$cFrontiers Media SA,$d[2016] 210 4$d©2016 215 $a1 online resource (72 pages) $cillustrations; digital file(s) 225 1 $aFrontiers Research Topics 300 $a"Published in: Frontiers in Neurology" -- front cover. 311 08$aPrint version: Plasticity in multiple sclerosis. [Lausanne, Switzerland] : Frontiers Media SA, ©2016 2889197646 320 $aIncludes bibliographical references. 327 $aEditorial: Plasticity in multiple sclerosis: from molecular to system level, from adaptation to maladaptation -- Microvesicles: what is the role in multiple sclerosis -- The neurophysiologist perspective into MS plasticity -- Brain plasticity effects of neuromodulation against multiple sclerosis fatigue -- The role of fMRI to assess plasticity of the motor system in MS -- Neuroplasticity and motor rehabilitation in multiple sclerosis -- Functional plasticity of the visual system in multiple sclerosis -- Network collapse and cognitive impairment in multiple sclerosis -- Case-based fMRI analysis after cognitive rehabilitation in MS: a novel approach -- Cognitive reserve as a useful concept for early intervention research in multiple sclerosis -- Measuring gray matter and white matter damage in MS: why this is not enough -- Clinical implications of neuroplasticity: the role of rehabilitation in multiple sclerosis 330 $aPlasticity occurs at multiple levels in multiple sclerosis (MS), from cells to synapses, from myelin to axons, from individual regions to large-scale brain networks. A growing body of evidence supports the notion that the course of MS and its extremely heterogeneous clinical manifestations might be the net result of disease burden and compensatory capacity. As a consequence, identifying what can be considered as "positive" plasticity and what, on the contrary, is a maladaptive reorganization is a very attractive goal which might help to develop therapeutic strategies able to promote the individual adaptive capacity. The aim of this Research Topic forum is to provide a state of the art update on the diversity of available data in humans with MS, derived from the many studies performed using different research tools, including immunological, neurophysiological and neuroimaging techniques which have addressed neuroplasticity at multiple system level, from motor, to visual, and cognitive. Synopsis of recent advances of plasticity research in MS aims to broaden the view across systems and techniques and to stimulate further studies on this emerging topic. 410 0$aFrontiers research topics. 517 3 $aPlasticity in MS 606 $aNeuroplasticity 606 $aMultiple sclerosis$xNeuroplasticity 606 $aMultiple sclerosis$xResearch 610 $aMultiple Sclerosis 610 $amotor 610 $acognitive 610 $aCompensation 610 $aNeurophysiological 610 $aplasticity 610 $aadaptation 610 $avisual 610 $areorganization 610 $afunctional magnetic resonance imaging 615 0$aNeuroplasticity. 615 0$aMultiple sclerosis$xNeuroplasticity. 615 0$aMultiple sclerosis$xResearch. 676 $a616.8 700 $aDaniel Zeller$4auth$01351520 702 $aZeller$b Daniel 702 $aRocca$b Maria A$g(Maria Assunta), 801 0$bUkMaJRU 906 $aBOOK 912 $a9910688342303321 996 $aPlasticity in multiple sclerosis$93114720 997 $aUNINA