LEADER 01866nam 2200373 450 001 9910688318103321 005 20230623205906.0 024 7 $a10.5772/intechopen.80180 035 $a(CKB)5400000000040848 035 $a(NjHacI)995400000000040848 035 $a(EXLCZ)995400000000040848 100 $a20230623d2020 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMelatonin $ethe hormone of darkness and its therapeutic potential and perspectives /$fMarilena Vlachou, editor 210 1$aLondon :$cIntechOpen,$d2020. 215 $a1 online resource (156 pages) 311 $a1-83962-910-X 320 $aIncludes bibliographical references. 330 $aThis book, on the pineal hormone melatonin, is addressed to a wide non-cognizant and cognizant readership. The hormone appears to be involved in sleep onset and other functions associated with the body's clock, the suprachiasmic nucleus. It is ubiquitous throughout both the animal and plant kingdoms and has a long evolutionary history as a hormone. Melatonin has a major role in the regulation of circadian rhythms in non-mammalian vertebrates and forms part of their control in mammals. The present text emphasizes the positive role of exogenously administered melatonin, and its synthetic derivatives, on disrupted circadian rhythm-related dysfunctions. This is effected by resetting the clock in jet lag sufferers and those with seasonal affective disorders, insomnia, and various neurological conditions. 517 $aMelatonin 606 $aMelatonin 615 0$aMelatonin. 676 $a612.492 702 $aVlachou$b Marilena 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910688318103321 996 $aMelatonin$92951504 997 $aUNINA