LEADER 02244nam 2200373 450 001 9910688312903321 005 20230623212609.0 024 7 $a10.5772/intechopen.73968 035 $a(CKB)5400000000041923 035 $a(NjHacI)995400000000041923 035 $a(EXLCZ)995400000000041923 100 $a20230623d2020 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aSarcoidosis and granulomatosis $ediagnosis and management /$fMohammad Hosein Motamedi, editor 210 1$aLondon :$cIntechOpen,$d2020. 215 $a1 online resource (178 pages) 311 $a1-83962-834-0 320 $aIncludes bibliographical references. 330 $aSarcoidosis is a multi-organ, granulomatous disease the etiology of which remains unknown. It is characterized by T-cell dysfunction and B-cell hyperactivity with increased local immune activity and inflammation that leads to the formation of noncaseating granulomas in the organs involved. The lung and lymphatic system are the most commonly affected organs, however virtually any organ may be affected. Other common sites of involvement include the skin, eye, central nervous system, and the heart. Patients may present different symptoms related to the disease stage and the specific organ involved. Sarcoidosis is a global disease, and its prevalence has increased twofold over the past years. Due to the clinical heterogeneity and variable diagnostic criteria in different countries, it is difficult to calculate the exact prevalence and incidence of sarcoidosis. Age, sex, race, and geographic origin significantly influence the incidence of sarcoidosis. The book at hand seeks to assess the current diagnostic techniques, imaging techniques, differential diagnosis of this disease, as well as other granulomatous diseases mimicking sarcoidosis. 517 $aSarcoidosis and Granulomatosis 606 $aSarcoidosis 615 0$aSarcoidosis. 676 $a616.429 702 $aMotamedi$b Mohammad Hosein 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910688312903321 996 $aSarcoidosis and granulomatosis$92951507 997 $aUNINA