LEADER 01804nam 2200337 450 001 9910688271803321 005 20230625131314.0 035 $a(CKB)5400000000046264 035 $a(NjHacI)995400000000046264 035 $a(EXLCZ)995400000000046264 100 $a20230625d2020 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aImmunosuppression /$fedited by Xuehui He 210 1$aLondon, United Kingdom :$cIntechOpen,$d2020. 215 $a1 online resource (104 pages) $cillustrations 311 $a1-83968-125-X 330 $aOur immune system is equipped with a series of defence mechanisms to recognise and respond to non-self molecules. Although essential for fighting off infections and preventing cancers, destructive immune responses pose a considerable challenge in autoinflammation and transplantation. Currently available immunosuppressants help to control destructive immune responses. However, management of side-effects of lifelong immunosuppression, including cancer development and reduced survival, remain major problems. For this reason, an increasing amount of interest is directed towards the natural specific regulatory mechanism of the immune system. A better understanding of these mechanisms holds the key. This book presents a comprehensive overview of immune suppression in transplantation, cancer and viral infections. Chapters cover modulation of Treg as well as the new era of immunotherapy. 606 $aImmunosuppression 615 0$aImmunosuppression. 676 $a615.9 702 $aHe$b Xuehui 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910688271803321 996 $aImmunosuppression$92054634 997 $aUNINA