LEADER 01842nam 2200373 450 001 9910688256803321 005 20230627032602.0 035 $a(CKB)5850000000050382 035 $a(NjHacI)995850000000050382 035 $a(EXLCZ)995850000000050382 100 $a20230627d2022 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aVitamin K $eRecent Topics on the Biology and Chemistry /$fedited by Hiroyuki Kagechika, Hitoshi Shirakawa 210 1$aLondon :$cIntechOpen,$d2022. 215 $a1 online resource (116 pages) $cillustrations 311 $a1-83969-393-2 320 $aIncludes bibliographical references. 330 $aVitamin K is a fat-soluble vitamin and a significant hydrophobic signaling molecule, like vitamins A and D. Besides its classical functions as a cofactor of ?-glutamyl carboxylase, which catalyzes the ?-carboxylation of vitamin K-dependent proteins, vitamin K has novel physiological and pharmacological activities that have been elucidated in the past two decades. The discovery of detailed action mechanisms of non-classical activities of vitamin K and the development of novel derivatives with unique structural and biological profiles would improve the understanding of vitamin K functions and clinical applications. This book discusses the biology and chemistry of vitamin K, which is helpful for fundamental and clinical investigations. 517 $aVitamin K 606 $aVitamins in human nutrition 615 0$aVitamins in human nutrition. 676 $a612.3 702 $aKagechika$b Hiroyuki 702 $aShirakawa$b Hitoshi 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910688256803321 996 $aVitamin K$92957213 997 $aUNINA