LEADER 01630nam 2200361 450 001 9910688146803321 005 20230626172514.0 035 $a(CKB)5580000000514622 035 $a(NjHacI)995580000000514622 035 $a(EXLCZ)995580000000514622 100 $a20230626d2022 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aGene Expression /$fFumiaki Uchiumi, editor 210 1$aLondon :$cIntechOpen,$d2022. 215 $a1 online resource (212 pages) 311 $a1-80355-623-4 330 $aGene expression is dependent on multiple steps, including transcription, RNA processing, and translation. Importantly, recent studies revealed that gene expression is regulated by chromatin structures and non-coding RNA profiles. Elucidating the molecular mechanisms may contribute to the development of novel therapeutics for aging-related diseases, including cancer and neurodegenerative diseases. This book provides a comprehensive overview of gene expression and its role in human disease. It consists of nine chapters organized into two sections on molecular mechanisms in controlling gene expression and the relationships between transcriptional control and human disease. 606 $aGenetic regulation 606 $aGene expression 615 0$aGenetic regulation. 615 0$aGene expression. 676 $a572.865 702 $aFumiaki Uchiumi 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910688146803321 996 $aGene expression$9795582 997 $aUNINA