LEADER 02212nam 2200373 450 001 9910687980503321 005 20230626035633.0 035 $a(CKB)5580000000514546 035 $a(NjHacI)995580000000514546 035 $a(EXLCZ)995580000000514546 100 $a20230626d2022 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aEvolving Concepts in Insulin Resistance /$fMarco Infante, editor 210 1$aLondon :$cIntechOpen,$d2022. 215 $a1 online resource (190 pages) 311 $a1-80355-503-3 327 $a1. The Insulin Journey in the Human Body -- 2. Insulin Receptor Isoforms in Physiology and Metabolic Disease -- 3. Molecular Mechanisms Involved in Insulin Resistance: Recent Updates and Future Challenges -- 4. Mechanisms of Insulin Resistance during Pregnancy -- 5. Dietary Activation of AMP-Activated Protein Kinase (AMPK) to Treat Insulin Resistance -- 6. Cardiac Natriuretic Peptide System: A Link between Adipose Tissue, Obesity, and Insulin Resistance -- 7. Berardinelli-Seip Syndrome: Report of an Old Case Successfully Treated with Anti-Glucocorticoid Therapy Followed by Bilateral Adrenalectomy. 330 $aOver the last decades, the growing prevalence of insulin resistance has dramatically contributed to the global epidemic of metabolic syndrome, obesity, type 2 diabetes mellitus, and cardiovascular disease. Therefore, there is an unmet need for novel nutritional and pharmacological strategies aimed to prevent or treat insulin resistance and its related comorbidities. This book presents a comprehensive overview of the pathophysiology and clinical consequences of insulin resistance in different settings, describing novel diagnostic biomarkers and molecular targets of this condition. 606 $aInsulin resistance 606 $aMetabolic syndrome 615 0$aInsulin resistance. 615 0$aMetabolic syndrome. 676 $a616.399 702 $aInfante$b Marco 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910687980503321 996 $aEvolving Concepts in Insulin Resistance$93014206 997 $aUNINA