LEADER 03540nam 2200481 450 001 9910686478403321 005 20230731000122.0 010 $a981-9903-61-0 024 7 $a10.1007/978-981-99-0361-0 035 $a(CKB)5840000000241919 035 $a(DE-He213)978-981-99-0361-0 035 $a(MiAaPQ)EBC7236573 035 $a(Au-PeEL)EBL7236573 035 $a(PPN)269660593 035 $a(EXLCZ)995840000000241919 100 $a20230731d2023 uy 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aPolymeric micelles $eprinciples, perspectives and practices /$fSachin Kumar Singh [and four others], editors 205 $a1st ed. 2023. 210 1$aSingapore :$cSpringer Nature Singapore Pte Ltd.,$d[2023] 210 4$dİ2023 215 $a1 online resource (XV, 294 p. 1 illus.) 311 $a981-9903-60-2 320 $aIncludes bibliographical references. 327 $a1. Synthesis, self-assembly and functional chemistry of Amphiphilic block copolymers -- 2. Advances in polymer optimisation for enhanced drug delivery -- 3. Dynamics of Micelle Formation -- 4. Types of Polymeric Micelles for Controlled Drug Release -- 5. Drug Solubilization and Drug Release from Polymeric Micelles -- 6. Physical and Analytical Techniques used for the Characterization of Polymeric Micelles -- 7.Stimuli-sensitive polymeric micelles for biomedical applications -- 8.Nucleic acid-based micellar therapy for the treatment of different diseases -- 9. Polymeric micelles in the delivery of therapeutic phytoconstituents -- 10. Diagnostic applications of surface-engineered polymeric micelles -- 11. Ligand conjugated polymeric micelles for targeted delivery of drug payloads in cancer therapy -- 12. Polymeric Micelles in the Delivery of Proteins -- 13. Regulatory aspects for polymeric micelles -- 14. Toxicological and regulatory challenges in design and development of polymeric micelles -- 15. Stability of polymeric micelles and their regulatory status. 330 $aThis book thoroughly reviews the advancements in design and applications of Polymeric Micelles (PMs) in drug delivery. It provides information on the synthesis of amphiphilic block copolymers and their types, functional chemistry for targeting and sensing, and biomedical applications. The book further provides the possibilities for designing PMs in a range of drug delivery approaches. The book addresses the molecular parameters of amphiphilic block copolymers that are required for functionalizing PMs for drug delivery applications. Additionally, the book presents recent advances in applications of PMs such as co-delivery, sensing, theranostics, delivery of nucleic acids, and proteins. Towards the end, it discusses different physico-chemical strategies to enhance the stability and drug retention of polymeric micelles and reviews the preclinical and clinical toxicity and immunogenicity-related aspects of polymeric micelles. This book is an invaluable source for academics, research, and industry professionals working in the field of polymeric micelles and drug delivery. 606 $aDrug delivery systems 606 $aNanomedicine 615 0$aDrug delivery systems. 615 0$aNanomedicine. 676 $a615.6 702 $aSingh$b Sachin Kumar 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910686478403321 996 $aPolymeric micelles$93417620 997 $aUNINA