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100   $a20230411d2023      u|         0
101 0 $aeng
135   $aurnn#008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aEngineering and Physical Approaches to Cancer /$fedited by Ian Y. Wong, Michelle R. Dawson
205   $a1st ed. 2023.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2023.
215   $a1 online resource (VIII, 331 pages, 60 illustrations, 57 illustrations in color) $cillustrations
225 1 $aCurrent Cancer Research,$x2199-2592
311 08$a3-031-22801-4 
320   $aIncludes bibliographical references and index.
327   $aChapter 1. EMT -- Chapter 2. Nuclear/Chromatin Mechanics -- Chapter 3. Cell level mechanical changes -- Chapter 4. Physical aspects related to metabolism -- Chapter 5. Mechanical tropism / Physical aspects of seed and soil -- Chapter 6. Tumor microenvironment interactions -- Chapter 7. Extracellular Matrix -- Chapter 8. Physical Assays Focused on Tumor Heterogeneity -- Chapter 9. Ecology / evolution of the tumor microenvironment -- Chapter 10. Spatial transcriptomics / proteomics in the Human Tumor Atlas.
330   $aEngineering and Physical Approaches to Cancer addresses the newest research at this interface between cancer biology and the physical sciences. Several chapters address the mechanobiology of collective and individual cell migration, including experimental, theoretical, and computational perspectives. Other chapters consider the crosstalk of biological, chemical, and physical cues in the tumor microenvironment, including the role of senescence, polyploid giant cells, TGF-beta, metabolism, and immune cells. Further, chapters focus on circulating tumor cells and metastatic colonization, highlighting both bioengineered models as well as diagnostic technologies. Further, this book features the work of emerging and diverse investigators in this field, who have already made impressive cross-disciplinary scientific contributions. This book is designed for a general audience, particularly researchers conversant in cancer biology but less familiar with engineering (and vice-versa). Thus, we envision that this book will be suitable for faculty, postdoctoral fellows, and advanced graduate students across medicine, biological sciences, and engineering. We also anticipate this book will be of interest to medical professionals and trainees, as well as researchers in the pharmaceutical and biomedical device industry.
410  0$aCurrent Cancer Research,$x2199-2592
606   $aCancer$xTreatment
606   $aCancer
606   $aCancer$xImaging
606   $aBiomechanics
606   $aCancer Therapy
606   $aCancer Microenvironment
606   $aCancer Imaging
606   $aBiomechanics
615  0$aCancer$xTreatment.
615  0$aCancer.
615  0$aCancer$xImaging.
615  0$aBiomechanics.
615 14$aCancer Therapy.
615 24$aCancer Microenvironment.
615 24$aCancer Imaging.
615 24$aBiomechanics.
676   $a612.76
676   $a616.99406
702   $aWong$b Ian Y.
702   $aDawson$b Michelle R.
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910686476203321
996   $aEngineering and Physical Approaches to Cancer$93089332
997   $aUNINA