LEADER 01881nam 2200349 450 001 9910678589503321 005 20230502070747.0 010 $a1-80356-600-0 035 $a(CKB)5840000000237831 035 $a(NjHacI)995840000000237831 035 $a(EXLCZ)995840000000237831 100 $a20230502d2023 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aEpilepsy $eSeizures without Triggers /$fKaneez Fatima Shad, editor 210 1$aLondon :$cIntechOpen,$d2023. 215 $a1 online resource (118 pages) 311 $a1-80356-599-3 330 $aAccording to the World Health Organization, nearly 80% of people with epilepsy live in low- and middle-income countries and could live seizure-free if properly diagnosed and treated. Among the structural and genetic triggers that may lead to epilepsy are head trauma, abnormal synaptic connectivity, receptor subunits anomalies, and atypical ionic channel function. Developing brains are specifically susceptible to seizures for many reasons, for example, the presence of enhanced excitation due to the early production of excitatory neurotransmitters, and the fact that the inhibitory neurotransmitter GABA causes excitation early in life. These studies help to clarify why the very young brain is exceptionally prone to seizures. The chapters presented in this book describe how structural, genetic, infectious, and metabolic abnormalities can lead to epileptogenesis. Nevertheless, many underlying disease mechanisms that can lead to epilepsy remain unknown. 606 $aEpilepsy 615 0$aEpilepsy. 676 $a616.853 702 $aShad$b Kaneez Fatima 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910678589503321 996 $aEpilepsy$92818881 997 $aUNINA