LEADER 04282nam  22006615  450 
001 9910678254403321
005 20251113175032.0
010   $a3-031-26859-8
024 7 $a10.1007/978-3-031-26859-5
035   $a(MiAaPQ)EBC7209288
035   $a(Au-PeEL)EBL7209288
035   $a(CKB)26240817400041
035   $a(DE-He213)978-3-031-26859-5
035   $a(PPN)269093435
035   $a(EXLCZ)9926240817400041
100   $a20230303d2023      u|         0
101 0 $aeng
135   $aurcnu||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aMetabolomics and Its Impact on Health and Diseases /$fedited by Veronica Ghini, Kathleen A. Stringer, Claudio Luchinat
205   $a1st ed. 2023.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2023.
215   $a1 online resource (384 pages)
225 1 $aHandbook of Experimental Pharmacology,$x1865-0325 ;$v277
311 08$aPrint version: Ghini, Veronica Metabolomics and Its Impact on Health and Diseases Cham : Springer International Publishing AG,c2023 9783031268588 
320   $aIncludes bibliographical references.
327   $aPreface -- Practical Aspects of NMR-Based Metabolomics -- Compound Identification in Mass Spectrometry-Based Metabolomics -- METABOLOMICS USING NMR ? Avoiding the ?Black-Box? -- Natural products drug discovery: on silica or in silico?- Quantitative NMR Methods in Metabolomics -- Advancements in pulsed stable isotope resolved metabolomics -- Metabolomics in Cell Biology -- NMR-based metabolomics to evaluate individual response to treatments -- Pharmacometabolomics of Asthma as a road map to Precision Medicine -- Prospective metabolomic studies in precision medicine -- Chemotherapy-induced Peripheral Neuropathy -- Metabolomics of Respiratory Diseases.
330   $aThis volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the NMR approaches are described in the chapters By David Wishart, Daniel Raftery and Ryan McKay, while mass spectrometry advances are covered by Charles R. Evans and Stefan Kempa. This book also reflects the state of the art in the application of metabolomics to cell biology (Marta Cascante and Ulrich Guenther) and chapters that share insights into the application of metabolomics in various diseases (Paola Turano and Claudio Luchinat, Rachel S. Kelly and JessicaLasky-Su, Paige Lacy, and Angela Rogers. Relationships of metabolomics with drugs are highlighted by Robert Verpoorte (natural products drug discovery), by Oscar Millet and by Turano and Luchinat (perspectives in precision medicine) and by Daniel L. Hertz (drug-induced peripheral neuropathy). From the above list of diverse topics, we believe this book has interdisciplinary appeal and scholars with an interest in the role of metabolomics in achieving precision medicine will find it of particular or special interest.
410  0$aHandbook of Experimental Pharmacology,$x1865-0325 ;$v277
606   $aPharmacology
606   $aBiochemical markers
606   $aCytology
606   $aAnalytical biochemistry
606   $aPharmacology
606   $aBiomarkers
606   $aCell Biology
606   $aAnalytical Biochemistry
615  0$aPharmacology.
615  0$aBiochemical markers.
615  0$aCytology.
615  0$aAnalytical biochemistry.
615 14$aPharmacology.
615 24$aBiomarkers.
615 24$aCell Biology.
615 24$aAnalytical Biochemistry.
676   $a780
702   $aGhini$b Veronica
702   $aStringer$b Kathleen A.
702   $aLuchinat$b Claudio
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910678254403321
996   $aMetabolomics and its impact on health and diseases$93375027
997   $aUNINA