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010   $a9783031224683$b(electronic bk.)
010   $z9783031224676
024 7 $a10.1007/978-3-031-22468-3
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035   $a(Au-PeEL)EBL7211138
035   $a(CKB)26240746100041
035   $a(DE-He213)978-3-031-22468-3
035   $a(PPN)269095748
035   $a(EXLCZ)9926240746100041
100   $a20230306d2023      u|         0
101 0 $aeng
135   $aurcnu||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aSleep and Clocks in Aging and Longevity /$fedited by Anita Jagota
205   $a1st ed. 2023.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2023.
215   $a1 online resource (552 pages)
225 1 $aHealthy Ageing and Longevity,$x2199-9015 ;$v18
311 08$aPrint version: Jagota, Anita Sleep and Clocks in Aging and Longevity Cham : Springer International Publishing AG,c2023 9783031224676 
320   $aIncludes bibliographical references and index.
327   $aSleep and circadian clock : Novel players in health impacts and Aging -- Cells and circuits of the suprachiasmatic nucleus and the control of circadian behaviour and sleep -- Circadian roles in sleep -- Age-related decline in the central circadian clock -- Cellular clocks in senescent cells -- Optimum sleep for healthy aging.
330   $aThis edited volume focuses on the interplay between sleep and circadian rhythms with health, aging and longevity. Sleep is absolutely important for human health and survival, as insufficient sleep is associated with a plethora of conditions, including the poor quality of life, onset of several diseases, and premature death. The sleep?wake cycle is an evolutionary conserved neurobiological phenomenon, and is a prominent manifestation of the biological clocks localised in the suprachiasmatic nucleus (SCN). Understanding bidirectional relationship between sleep and circadian rhythms is of utmost importance and urgency, especially in the context of modern lifestyle where sleep is often out of phase with the internal body clocks, social jetlag, artificial lights and so on. The 25 chapters by leading researchers and experts from 11 countries are arranged into seven sections: understanding sleep and clock interlink in health and longevity; sleep, aging and longevity; clock, aging and longevity; melatonin, sleep and clock; genetic regulation of sleep and clock; therapeutic interventions in sleep disorders and clock misalignment; and experimental models to study sleep and clocks in aging and longevity. This book is useful for advanced undergraduate and graduate students, and researchers, educators, and other biomedical professionals. .
410  0$aHealthy Ageing and Longevity,$x2199-9015 ;$v18
606   $aAging
606   $aCytology
606   $aCircadian rhythms
606   $aNeurosciences
606   $aMedicine$xResearch
606   $aBiology$xResearch
606   $aAgeing
606   $aCellular Circadian Rhythms
606   $aNeuroscience
606   $aBiomedical Research
615  0$aAging.
615  0$aCytology.
615  0$aCircadian rhythms.
615  0$aNeurosciences.
615  0$aMedicine$xResearch.
615  0$aBiology$xResearch.
615 14$aAgeing.
615 24$aCellular Circadian Rhythms.
615 24$aNeuroscience.
615 24$aBiomedical Research.
676   $a612.67
676   $a612.67
702   $aJagota$b Anita
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
912   $a9910678252203321
996   $aSleep and Clocks in Aging and Longevity$93071682
997   $aUNINA