LEADER 09203nam 2200529 450 001 9910677887603321 005 20230629222903.0 010 $a1-118-97597-9 010 $a1-118-97599-5 010 $a1-118-97607-X 035 $a(CKB)4330000000007808 035 $a(MiAaPQ)EBC6577246 035 $a(Au-PeEL)EBL6577246 035 $a(OCoLC)1249473528 035 $a(EXLCZ)994330000000007808 100 $a20211210d2021 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHandbook of diabetes /$fRudy Bilous, Richard Donnelly, Iskandar Idris 205 $a5th ed. 210 1$aHoboken, New Jersey :$cWiley Blackwell,$d[2021] 210 4$d©2021 215 $a1 online resource (307 pages) 311 $a1-118-97604-5 327 $aCover -- Title Page -- Copyright Page -- Contents -- Preface -- Key to the boxes -- List of abbreviations -- Part 1 Introduction to diabetes -- Chapter 1 Introduction to diabetes -- Further Reading -- Chapter 2 History of diabetes -- Further Reading -- Chapter 3 Diagnosis and classification of diabetes -- Intermediate categories of hyperglycaemia: Pre-diabetes -- Classification of diabetes -- FURTHER READING -- Chapter 4 Public health aspects of diabetes -- Primary prevention of Type 2 Diabetes -- Providing access to structured diabetes education -- Improving diabetes treatment and care -- Commissioning diabetes services -- Further Reading -- Chapter 5 Normal physiology of insulin secretion and action, and the incretin effect -- Islet structure and function -- Insulin synthesis and insulin polypeptide structure -- Insulin secretion -- The incretin effect -- Insulin receptor signalling -- The family of GLUT transporters -- Further Reading -- Chapter 6 Epidemiology and aetiology of type 1 diabetes -- Introduction -- Epidemiology -- Aetiology -- Genetics -- Environmental and maternal factors -- Viruses -- Apoptosis -- Dietary factors -- Toxins -- Animal models -- Hygiene hypothesis -- Accelerator hypothesis -- Further Reading -- Chapter 7 Epidemiology and aetiology of type 2 diabetes -- Prevalence rates and global burden -- Urban versus rural -- Impaired glucose tolerance -- Incidence -- Risk factors for type 2 diabetes -- Conclusion -- FURTHER READING -- Chapter 8 Other types of diabetes -- Introduction -- Monogenic Diabetes and association with other Inherited Conditions -- Other monogenic causes -- Pancreatic disease -- Diabetes complicating other endocrine diseases -- Medication associated diabetes -- Further Reading -- Part 2 Metabolic control and complications -- Chapter 9 Diabetes control and its measurement -- Introduction. 327 $aCapillary blood glucose monitoring -- Urine glucose monitoring -- Glycated haemoglobin -- IFCC standard -- Estimated average glucose (eAG) -- Glucose variability -- Fructosamine -- Urine and blood ketone measurements -- Continuous glucose monitoring (CGM) systems -- Further Reading -- Chapter 10 Management of type 1 diabetes -- Insulin replacement -- Intensive insulin therapy -- Diet and Carbohydrate counting -- Glycaemic targets -- Continuous subcutaneous insulin infusion -- Further Reading -- Chapter 11 Management of type 2 diabetes -- FURTHER READING -- Chapter 12 Diabetic ketoacidosis (DKA), hyperglycaemic hyperosmolar state (HHS) and lactic acidosis -- Precipitating factors for diabetic ketoacidosis -- Pathophysiology -- Treatment -- Complications of diabetic ketoacidosis -- Hyperosmolar hyperglycaemic state -- Lactic acidosis -- Further Reading -- Chapter 13 Hypoglycaemia -- FURTHER READING -- Chapter 14 Causes of complications -- Hyperglycaemia -- Blood pressure -- Metabolic memory -- How does hyperglycaemia cause tissue complications? -- Further Reading -- Chapter 15 Diabetic eye disease -- Pathology and clinical appearances -- Factors associated with the development of retinopathy -- Classification of retinopathy -- Treatment of retinopathy -- Surveillance and screening -- Further Reading -- Chapter 16 Diabetic nephropathy -- Natural history -- Stages of nephropathy -- Epidemiology -- Screening for nephropathy -- Pathology and pathophysiology -- Risk factors for nephropathy -- Management -- Is it diabetic nephropathy? -- Further Reading -- Chapter 17 Diabetic neuropathy -- Chronic sensorimotor neuropathy -- Further Reading -- Chapter 18 Blood lipid abnormalities -- Further reading -- Chapter 19 Hypertension in diabetes -- Causative links -- Definition of hypertension and targets -- Diagnosis of hypertension -- Management -- FURTHER READING. 327 $aChapter 20 Macrovascular disease in diabetes -- Atherosclerosis -- Glycaemic vascular injury -- FURTHER READING -- Chapter 21 Foot problems in diabetes -- FURTHER READING -- Chapter 22 Sexual problems in diabetes -- FURTHER READING -- Chapter 23 Gastrointestinal problems in diabetes -- Symptoms -- Oesophagus -- Gastroparesis -- Small bowel -- Large bowel -- Abdominal pain -- Gut microbiota -- Further Reading -- Chapter 24 Non-alcoholic liver disease (NAFLD) -- Introduction -- Definition -- Risk factors for NAFLD -- NAFLD and diabetes -- Screening -- Management -- Thiazolidinediones -- Glucagon-like peptide-1 analogs and DPP-4 inhibitors -- Sodium Glucose cotransporter 2 inhibitors -- Vitamin E -- Bariatric surgery -- Statins -- FURTHER READINGS -- Chapter 25 Diabetes and cancer -- Introduction -- Epidemiology -- Possible biological mechanisms -- Effect of diabetes on cancer mortality and treatment -- Effects of cancer therapy on diabetes -- Effects of diabetes therapies on cancer incidence and progression -- FURTHER READING -- Chapter 26 Skin and connective tissue disorders in diabetes -- Diabetic dermopathy -- Necrobioisis lipoidica diabetocorum -- Acanthosis nigricans -- Diabetic bullae -- Granuloma annulare -- Skin thickening, waxy skin, and stiff joints -- Other skin conditions -- FURTHER READING -- Chapter 27 Psychological and psychiatric problems in diabetes -- Depression and anxiety -- Diabetes distress -- Cognitive changes -- Severe Mental Illness -- Published guidance. -- FURTHER READING -- Part 3 The spectrum and organisation of diabetes care -- Chapter 28 Intercurrent situations that affect diabetes control -- Exercise -- Drugs -- Infections -- Enteral feeding -- Surgery and critical intercurrent illness -- FURTHER READING -- Chapter 29 Pregnancy and diabetes -- Effects of pregnancy on the woman with diabetes. 327 $aEffects of maternal diabetes on the pregnancy -- Management of pregnancy in diabetes -- Gestational diabetes -- Contraception -- FURTHER READING -- Chapter 30 Diabetes in childhood and adolescence -- FURTHER READING -- Chapter 31 Diabetes in old age -- FURTHER READING -- Chapter 32 Diabetes and lifestyle -- Introduction -- Smoking -- Alcohol -- Drug and substance abuse -- Driving -- Employment -- Travel and leisure activities. -- FURTHER READING -- Chapter 33 Organisation of diabetes care: integrating diabetes service -- What is integrated diabetes care? -- What are the essential components to an integrated diabetes service? -- Impact of COVID-19 pandemic: lessons on organizing diabetes care -- FURTHER READING -- Chapter 34 Transplantation and stem cell therapy -- Pancreas transplantation -- Islet cell transplantation -- Xenotransplantation -- Stem cell therapy -- Gene therapy -- Index -- EULA. 330 $a"For over 20 years, our Handbook of Diabetes has been the perfect practical companion to its parent Textbook of Diabetes, one of Wiley's key medical copyrights and widely considered the most clinically-focused diabetes reference book. Cheaper, more practical/accessible, and less scientifically dense than reference books, the Handbook of Diabetes is perfect reading for all health professionals with an interest in diabetes, especially doctors in speciality diabetes/endocrinology training, foundation level doctors, diabetes specialist nurses, and GPs. Its focus is clearly on the clinical aspects of the disease and in particular, how to best manage patients suffering from diabetes. As well is the strong emphasis on the clinical, readers love its visual look and high production standards. Clear and easy-to-navigate, it's packed full of case histories, key learning/practice points, landmark clinical trials and additional resources to consult in every chapter, and benefits from a well-designed and full colour interior throughout. To support the text, over 400 figures, including 300 beautifully drawn colour diagrams provide the reader with a visual element unmatched in other diabetes handbooks"--$cProvided by publisher. 606 $aDiabetes 606 $aDiabetes$xComplications 615 0$aDiabetes. 615 0$aDiabetes$xComplications. 676 $a616.462 700 $aBilous$b Rudy W.$0932373 702 $aDonnelly$b Richard$f1960- 702 $aIdris$b Iskandar 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910677887603321 996 $aHandbook of diabetes$93071796 997 $aUNINA LEADER 01529oem 2200433Ia 450 001 9910696353603321 005 20080117131116.0 035 $a(CKB)5470000002377295 035 $a(OCoLC)70665305 035 $a(EXLCZ)995470000002377295 100 $a20060721d2006 ca 101 0 $aeng 120 $ab|||||||||||| 121 $a||||||||| 124 $bd 135 $aurcnu--|m|||| 181 $ccrd$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aDatabase for the geologic map of the Chelan 30-minute by 60-minute quadrangle, Washington (I-1661)$b[electronic resource] /$fby R.W. Tabor ... 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