LEADER 02910nam 2200433 450 001 9910677344203321 005 20230126215505.0 010 $a1-119-91327-6 010 $a1-119-69173-7 010 $a1-119-69170-2 035 $a(MiAaPQ)EBC7045610 035 $a(Au-PeEL)EBL7045610 035 $a(CKB)24265995800041 035 $a(EXLCZ)9924265995800041 100 $a20221231d2022 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aFundamentals of drug development /$fJeffrey S. Barrett 210 1$aHoboken, New Jersey :$cWiley,$d[2022] 210 4$dİ2022 215 $a1 online resource (512 pages) 320 $aIncludes bibliographical references and index. 327 $aThe history of drug development -- The modern pharmaceutical industry : big and small pharma, biotechnology companies, and generic drug makers -- Legal considerations, intellectual property, patents and patent protection -- The global regulatory landscape -- Phases of drug development : old and new paradigms -- Discovery / preclinical -- Phase I -- Phase II -- Phase III -- Phase IV, special populations and post marketing commitments -- Role and function of project teams -- Compound progression and go / no go criteria -- Regulatory milestones and the submission process -- Life cycle management -- Formulation development -- Chemistry and manufacturing (CMC) -- Health economics and the healthcare industry -- Current state of affairs : attrition rates and evolving corporate strategies -- Medical devices -- Distribution and the supply chain -- Sales, marketing and advertising -- Generic drugs and the generic industry -- The generic approval process -- Data sharing and collaboration -- The future of the pharmaceutical industry. 330 $a"This book discusses how to conduct pharmaceutical research and the context for how the industry fits into global healthcare. Holistically, the well-qualified author helps readers and students of drug development appreciate the time and expense of the process. Specifically, the work identifies the emerging trends shaping the future of drug development, along with important related topics like generic drugs, data sharing, and collaboration. To aid in seamless reader comprehension, the book includes a glossary of terms and a self-assessment quiz for each chapter at the end. PowerPoint slides are also available as an online ancillary for adopting professors"--$cProvided by publisher. 410 0$aWiley Online Library ebooks. 606 $aPharmacology 615 0$aPharmacology. 676 $a615.10724 700 $aBarrett$b Jeffrey S.$01345072 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910677344203321 996 $aFundamentals of drug development$93070469 997 $aUNINA