LEADER 03386nam  2200853z- 450 
001 9910674395803321
005 20220111
035   $a(CKB)5400000000042115
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/77041
035   $a(oapen)doab77041
035   $a(EXLCZ)995400000000042115
100   $a20202201d2021      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aRole of TCTP in Cell Biological and Disease Processes
210   $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021
215   $a1 online resource (150 p.)
311 08$a3-0365-2285-9 
311 08$a3-0365-2286-7 
330   $aTranslationally controlled tumor protein (TCTP), also referred to as HRF or fortilin, is a multifunctional protein, expressed in all eukaryotic organisms from protozoa to humans. TCTP is involved in many basic biological processes, such as cell division, growth, and development. It is therefore not surprising that dysregulation of TCTP occurs in various disease processes, such as cardiovascular, allergic, and immune disorders. TCTP's role in cancer-promoting pathways is well- documented, and the protein is considered a potential target for the design of new anti-cancer strategies. Therefore, an understanding of the core biological functions of TCTP, the mechanisms underlying its cellular regulation, and its involvement in disease processes is important. This book provides a current overview on the basic biological functions of TCTP and on its role in promoting a range of disease processes.
606   $aBiology, life sciences$2bicssc
606   $aResearch and information: general$2bicssc
610   $aallergy
610   $aapoptosis
610   $aautophagy
610   $abasophils
610   $abiological stress reactions
610   $abrown spider
610   $acancer
610   $acardiovascular diseases
610   $aconditional knockout mice
610   $adevelopment
610   $aDHA
610   $aFc?RI
610   $afortilin)
610   $agrowth and development
610   $aHER2-positive breast cancer
610   $aHRF
610   $aIgE
610   $aLoxosceles
610   $amast cells
610   $aMmi1
610   $an/a
610   $aNestin-cre
610   $aneurogenesis
610   $aneuronal progenitor cells
610   $anitrogen starvation
610   $aperinatal death
610   $aphospho-TCTP
610   $aproliferation
610   $arapamycin
610   $areactive oxygen species
610   $aregulated protein degradation
610   $aregulation of protein synthesis
610   $aT-DM1
610   $aTCTP
610   $aTCTP (HRF
610   $atoxin
610   $atranslationally controlled tumor protein
610   $atranslationally controlled tumor protein (TCTP)
610   $avenom
615  7$aBiology, life sciences
615  7$aResearch and information: general
700   $aBommer$b Ulrich-Axel$4edt$01338462
702   $aKawakami$b Toshiaki$4edt
702   $aBommer$b Ulrich-Axel$4oth
702   $aKawakami$b Toshiaki$4oth
906   $aBOOK
912   $a9910674395803321
996   $aRole of TCTP in Cell Biological and Disease Processes$93058560
997   $aUNINA