LEADER 01530cam2-2200505---450 001 990000389930203316 005 20180308150858.0 010 $a88-16-30035-3 035 $a0038993 035 $aUSA010038993 035 $a(ALEPH)000038993USA01 035 $a0038993 100 $a20010404h1991----|||y0itay0103----ba 101 0 $aita 102 $aITA 105 $a||||||||001yy 200 1 $aNello spazio della metafisica$el'epoca moderna$fHans Urs von Balthasar$gtrad. di Guido Sommavilla 205 $a2. ed. 210 $aMilano$cJaca book$d1991 215 $a599 p. 225 $aGià e non ancora$v35 312 $aIm Raum der Metaphysik 410 $12001$aGià e non ancora$v35 454 $12001$aIm Raum der Metaphysik$91500061 461 1$10010001862$12001$aGloria$euna estetica teologica 676 $a230. 700 1$aBALTHASAR,$bHans Urs, von$0452111 702 1$aSOMMAVILLA,$bGuido 801 $aIT$bSALBC$gISBD 912 $a990000389930203316 951 $aII.2. 2512/5(XIV 1072 /5)$b149602 L.M.$cXIV 1072/ 5 951 $aAA 261.51 BAL$b8735 FIL 959 $aBK 969 $aUMA 969 $aFIL 979 $aPATTY$b90$c20010404$lUSA01$h1214 979 $c20020403$lUSA01$h1647 979 $aPATRY$b90$c20040406$lUSA01$h1627 979 $aCOPAT1$b90$c20050518$lUSA01$h1129 979 $c20121027$lUSA01$h1542 979 $c20121027$lUSA01$h1607 979 $c20121027$lUSA01$h1610 996 $aIm Raum der Metaphysik$91500061 997 $aUNISA DEB $aSA0025450 LEADER 02387nam 2200337 450 001 9910674394903321 005 20230629090929.0 035 $a(CKB)4920000000094856 035 $a(NjHacI)994920000000094856 035 $a(EXLCZ)994920000000094856 100 $a20230629d2018 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMolecular Pathways of Estrogen Receptor Action /$fedited by Farzed Pakdel 210 1$aBasel :$cMDPI - Multidisciplinary Digital Publishing Institute,$d2018. 215 $a1 online resource (304 pages) $cillustrations 311 $a3-03897-296-7 330 $aEstrogen receptors (ERs) are typical members of the superfamily of nuclear receptors that mainly function as ligand-inducible transcription factors that bind chromatin, as homodimers, at specific response elements. A tight reciprocal coupling between rapid 'non-genomic' and 'genomic' ER actions may also occur in many physiological processes. ERs have long been evaluated for their roles in controlling the expression of genes involved in vital cellular processes such as proliferation, apoptosis, and differentiation. Therefore, given the various and pleiotropic functions of ERs, the dysregulation of their pathways contributes to several diseases such as the hormone-dependent breast; endometrial and ovarian cancers; and neurodegenerative diseases, cardiovascular diseases, and osteoporosis. In this printed edition of the Special Issue, "Molecular Pathways of Estrogen Receptor Action", promising results on understanding the mechanisms underlying ER-mediated effects in various pathophysiological processes are represented, covering different roles of ER pathways in the tumorigenesis, the resistance to endocrine therapy, the dynamics of 3D genome organization, and cross-talk with other signaling pathways. This Special Issue also provides insight into the emerging roles of estrogen-signaling pathways in lung cancer, the tumor microenvironment, and the immune system. 606 $aEstrogen$xReceptors 615 0$aEstrogen$xReceptors. 676 $a573.44 702 $aPakdel$b Farzed 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910674394903321 996 $aMolecular Pathways of Estrogen Receptor Action$92932984 997 $aUNINA