LEADER 01117nam a22002651i 4500 001 991002387029707536 005 20030610160832.0 008 030925s1940 it |||||||||||||||||ita 035 $ab12281566-39ule_inst 035 $aARCHE-032913$9ExL 040 $aBiblioteca Interfacoltà$bita$cA.t.i. Arché s.c.r.l. Pandora Sicilia s.r.l. 082 04$a591.188 100 1 $aLaporta, Michele$0453288 245 10$aComportamento della protrombina nell'ittero da occlusione sperimentale /$cdi M. Laporta 260 $a[Napoli] :$b[V. Idelson],$c[1940] 300 $a1 v. ;$c25 cm 500 $aEstr. da: Bollettino della Società italiana di biologia sperimentale, v. 15, fasc. 10(1940) 650 4$aFisiologia 650 4$aBiologia$xRicerca sperimentale 907 $a.b12281566$b02-04-14$c08-10-03 912 $a991002387029707536 945 $aLE002 Busta B 87/30$g1$i2002000778024$lle002$o-$pE0.00$q-$rl$s- $t0$u0$v0$w0$x0$y.i12674229$z08-10-03 996 $aComportamento della protrombina nell'ittero da occlusione sperimentale$9165013 997 $aUNISALENTO 998 $ale002$b08-10-03$cm$da $e-$fita$git $h0$i1 LEADER 02340nam 2200361 450 001 9910674373603321 005 20230629135247.0 035 $a(CKB)4920000000094777 035 $a(NjHacI)994920000000094777 035 $a(EXLCZ)994920000000094777 100 $a20230629d2018 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aAdvances in micro-bioreactor design for organ cell studies /$fedited Carl-Fredrik Mandenius 210 1$aBasel, Switzerland :$cMDPI - Multidisciplinary Digital Publishing Institute,$d[2018] 210 4$d©2018 215 $a1 online resource (vii, 157 pages) $cillustrations 311 $a3-03897-233-9 320 $aIncludes bibliographical references. 330 $aMicro-bioreactors offer unique opportunities to study biological systems under fluidic conditions. The concept of micro-bioreactors suggests that biological reaction conditions at a large scale can be scaled down to micro-volumes while maintaining performance and functionality. Models and operation principles can be simulated at a smaller scale, either by scaling down organs in the human body, or bioreactors for the production of biologics. This book highlights these issues with much focus on new engineering design approached. Initial chapters cover conceptual design of microbioreactors and organ-on-chips, and the role of microbioreactors in tissue engineering for the clinical and for therapeutic targets. Two chapters are dedicated to microbioreactors for implementing tumour models. Other chapters discuss three-dimensional models for hepatic and cardiac cells for toxicity testing and drug evaluation. Finally, the design of organ chips for cartilage scaffolds and integration of sensors are covered in separate chapters. We believe the book have substantial value for researchers active in bioreactor engineering, drug development and cell physiology as well as readers interested in the these topics. 606 $aBioreactors 615 0$aBioreactors. 676 $a660.6 702 $aMandenius$b Carl-Fredrik 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910674373603321 996 $aAdvances in Micro-Bioreactor Design for Organ Cell Studies$92932998 997 $aUNINA