LEADER 03247nam 2200373 450 001 9910674035403321 005 20230624081252.0 035 $a(CKB)5400000000043549 035 $a(NjHacI)995400000000043549 035 $a(EXLCZ)995400000000043549 100 $a20230624d2022 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aSpecial Issue in Honor of Professor James D. McChesney on the Occasion of his 80th Birthday /$fMuhammad Ilias and Dhammika Nanayakkara 210 1$aBasel, Switzerland :$cMDPI - Multidisciplinary Digital Publishing Institute,$d2022. 215 $a1 online resource (262 pages) 311 $a3-0365-2712-5 330 $aPlants have been the sources of important pharmaceuticals, flavoring agents, and agrochemicals. The antimalarial drugs artemisinin and quinine; the anticancer drugs taxol, etoposide, and vinca alkaloids; the sugar-free sweetening agents stevioside and rebaudiosides; and antifeedant azadiractin are good examples of important plant-based drugs, food additives, and agrochemicals currently on the market. Despite these and many other successes, there are significant challenges to discovering and developing commercially important natural products from plants, such as procuring plant materials in large quantities, separating active constituents from complex mixtures, and undesirable qualities, such as low solubility or poor chemical or metabolic stability of active constituents. Dr. James D. McChesney has contributed immensely to overcoming the inherent challenges associated with discovering and developing products modeled from plant-based natural product leads. His research on artemisinin, taxol, galanthamine, podophyllotoxin, and stevia sweet glycosides exemplifies the magnitude of these contributions. His extensive work on the structural modification of taxol led to the discovery and development of the anticancer agent TPI 287, a third-generation taxane analog that is currently undergoing clinical trials. Dr. McChesney has had a long, distinguished teaching and research career, has authored more than 225 research publications, and holds more than 60 patents. He is a past president and Fellow of the American Society of Pharmacognosy and a Fellow of the AAAS. He has mentored many graduate students, post-docs, and junior faculty members who hold prominent positions in natural products research establishments in the US and worldwide. We wish to dedicate this Special Issue Book Version to celebrate the eightieth birthday of Dr. McChesney, a prolific thinker with abundant inventiveness in the field of natural product chemistry and pharmacognosy. 606 $aLife sciences$xStudy and teaching 606 $aBiology$xStudy and teaching 615 0$aLife sciences$xStudy and teaching. 615 0$aBiology$xStudy and teaching. 676 $a570.76 700 $aIlias$b Muhammad$01367476 702 $aNanayakkara$b Dhammika 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910674035403321 996 $aSpecial Issue in Honor of Professor James D. McChesney on the Occasion of his 80th Birthday$93390720 997 $aUNINA