LEADER 02544nam 2200337 450 001 9910674035003321 005 20230624061130.0 035 $a(CKB)4100000001283626 035 $a(NjHacI)994100000001283626 035 $a(EXLCZ)994100000001283626 100 $a20230624d2017 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aLC-MS/MS Method for Mycotoxin Analysis /$fAldo Lagana?, editor 210 1$aBasel, Switzerland :$cMDPI AG - Multidisciplinary Digital Publishing Institute,$d2017. 215 $a1 online resource (194 pages) 311 $a3-03842-606-7 330 $aAnnotation Mycotoxins are secondary metabolites produced by some species of filamentous fungi belonging to Fusarium, Aspergillus, Penicillium, Claviceps and Alternaria genera. The biochemical significance of mycotoxins in fungal metabolism has not always been fully clarified; however, the main concern for mycotoxins is driven by the deleterious effects they can exert on human and animal health. Structurally, the mycotoxins currently known belong to heterogeneous chemical classes, therefore the toxic effects they can induce are highly diverse (e.g., cancerogenic and immunosuppressive effects). The main route of human exposure to mycotoxins is by intake of contaminated food, either directly from contaminated agricultural products, or indirectly from residues and metabolites present in foods of animal origin. Immunochemical methods are generally used for the fast screening of mycotoxin presence; however, for confirmation purposes, analytical methods based on high-performance liquid chromatography (LC) are preferred, especially when coupled with tandem mass spectrometry (MS/MS), which allows the determination of multiclass mycotoxins in a single analysis. Moreover, the technical innovations available in LC-MS/MS instrumentation are prompting its application to the monitoring of contaminants in food and feed. The aim of this paper collection, constituted by ten research articles and one review, is to provide the reader with an overview on the novelties and capabilities in LC-MS/MS-based multi-mycotoxin methods, also including the investigation of emerging and modified mycotoxins. 606 $aMycotoxins 615 0$aMycotoxins. 676 $a615.95295 702 $aLagana?$b Aldo 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910674035003321 996 $aLC-MS$92936244 997 $aUNINA LEADER 01781nam 2200469I 450 001 9910703814203321 005 20150820144629.0 035 $a(CKB)5470000002435593 035 $a(OCoLC)918989560 035 $a(EXLCZ)995470000002435593 100 $a20150820j201503 ua 0 101 0 $aeng 135 $aurbn||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEvaluation of the 7-km GEOS-5 nature run /$fRonald Gelaro [and twenty-seven others] 210 1$aGreenbelt, Maryland :$cNational Aeronautics and Space Administration, Goddard Space Flight Center,$dMarch 2015. 215 $a1 online resource (xiv, 285 pages) $ccolor illustrations, maps 225 1 $aNASA/TM ;$v2014-104606.$aTechnical report series on global modeling and data assimilation ;$vvolume 36 300 $aTitle from title screen (viewed Aug. 20, 2015). 300 $a"March 2015." 320 $aIncludes bibliographical references (pages 276-285). 517 3 $aEvaluation of the 7-km Goddard Earth Observing System-5 nature run 606 $aAtmospheric General Circulation Models$2nasat 606 $aEarth Observing System (EOS)$2nasat 606 $aHydrological cycle$2nasat 606 $aMarine meteorology$2nasat 606 $aMesoscale phenomena$2nasat 615 7$aAtmospheric General Circulation Models. 615 7$aEarth Observing System (EOS) 615 7$aHydrological cycle. 615 7$aMarine meteorology. 615 7$aMesoscale phenomena. 700 $aGelaro$b Ronald$01416591 712 02$aGoddard Space Flight Center, 801 0$bGPO 801 1$bGPO 906 $aBOOK 912 $a9910703814203321 996 $aEvaluation of the 7-km GEOS-5 nature run$93522456 997 $aUNINA