LEADER 00432nam  2200169z- 450 
001 9910671933303321
035   $a(CKB)5590000000917492
035   $a(EXLCZ)995590000000917492
100   $a20220614c2022uuuu  -u-            -
101 0 $aeng
200 00$aAção civil pública
210   $cEditora Processo
311   $a9786553780194 
906   $aBOOK
912   $a9910671933303321
996   $aAção civil pública$93051848
997   $aUNINA

LEADER 02404oam  2200505   450 
001 9910787329803321
005 20190911103513.0
010   $a0-429-07190-6
010   $a1-4665-7221-3
024 7 $a10.1201/b16259
035   $a(OCoLC)868928102
035   $a(MiFhGG)GVRL8QEG
035   $a(EXLCZ)992670000000394354
100   $a20130920h20142014  uy             0
101 0 $aeng
135   $aurun|---uuuua
181   $ctxt
182   $cc
183   $acr
200 10$aAnalysis of complex diseases $ea mathematical perspective /$fGuanyu Wang
210  1$aBoca Raton :$cCRC Press, Taylor & Francis Group,$d[2014]
210  4$d?2014
215   $a1 online resource (xxi, 196 pages) $cillustrations (some color)
225 0 $aGale eBooks
300   $aDescription based upon print version of record.
311   $a1-4665-7223-X 
320   $aIncludes bibliographical references.
327   $aFood intake and energy metabolism -- Glucose homeostasis -- Optimal glucose homeostasis -- Bistability as a fundamental phenomenon -- Biomolecular network -- P13K-AKT-TOR pathway -- Diseases related to metabolism -- Mathematical modeling of the P13K-AKT-TOR Pathway -- Fundamental decomposition -- Normal phenotype -- Disease phenotypes -- Tao of diseases.
330   $aA complex disease involves many etiological and risk factors operating at multiple levels-molecular, cellular, organismal, and environmental. The incidence of such diseases as cancer, obesity, and diabetes are increasing in occurrence, urging us to think fundamentally and use a broader perspective to identify their connection and revolutionize treatments. The understanding of biological data derived from studying diseases can be enhanced by theories and mathematical models, which clarify the big picture and help to reveal the overarching mechanisms that govern complex biological phenomena.<
606   $aMetabolism$xDisorders
606   $aSystems biology
606   $aBiological models
606   $aGenetic disorders
615  0$aMetabolism$xDisorders.
615  0$aSystems biology.
615  0$aBiological models.
615  0$aGenetic disorders.
676   $a616.3/9
700   $aWang$b Guanyu$c(Physicist),$01584767
801  0$bMiFhGG
801  1$bMiFhGG
906   $aBOOK
912   $a9910787329803321
996   $aAnalysis of complex diseases$93868735
997   $aUNINA