LEADER 03926nam 22005655 450 001 9910647788403321 005 20230131070130.0 010 $a981-19-8225-2 024 7 $a10.1007/978-981-19-8225-5 035 $a(MiAaPQ)EBC7188479 035 $a(Au-PeEL)EBL7188479 035 $a(CKB)26076436700041 035 $a(DE-He213)978-981-19-8225-5 035 $a(PPN)267812469 035 $a(EXLCZ)9926076436700041 100 $a20230131d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPathobiology of Parasitic Protozoa: Dynamics and Dimensions$b[electronic resource] /$fedited by Budhaditya Mukherjee, Arijit Bhattacharya, Rupkatha Mukhopadhyay, Bruno Guedes Alcoforado Aguiar 205 $a1st ed. 2023. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2023. 215 $a1 online resource (230 pages) 311 08$aPrint version: Mukherjee, Budhaditya Pathobiology of Parasitic Protozoa: Dynamics and Dimensions Singapore : Springer,c2023 9789811982248 320 $aIncludes bibliographical references and index. 327 $a1.Nanotechnology-based promising therapeutic approaches against protozoan -- 2. Intertwining of retinoic acid and cholesterol pathway and its consequences in Leishmania donovani infected macrophages -- 3. Role and pathophysiology of protozoan parasites causing liver diseases -- 4. Cognitive Impairment in Parasitic Protozoan Infection -- 5. Cycling Within a Cell: Cell Cycle of Intracellular Kinetoplastid Parasites -- 6. Elaborating role of aspartyl protease in host modulation and invasion in Apicomplexan parasites Plasmodium and Toxoplasma -- 7. Leishmaniasis: Tissue tropism in relation to the species diversity -- 8. Transcriptional control in Entamoeba: Something old, Something new -- 9. A perspective on mathematical modeling and machine learning models to predict Visceral Leishmaniasis -- 10. Elucidating the Role of miRNA in Inflammasome Mediated Immune Response in Leishmaniasis -- 11. An Insight into Immunopathology of Leishmaniasis. 330 $aThis book illustrates the importance and significance of the systems approach in deciphering diverse aspects of host-parasite interactions in infection dynamics. It describes the complex issues and state-of-the-art progress in the infection biology of parasitic protozoa. The book explores the current concepts and paradigms of gene expression, metabolome, and immune remodeling in these diseases. The chapters encompass updates on the parasitic tropism, co-evolution, systemic responses in hosts, and translational approaches. It provides an overview of the parasite's efficient ways of exploiting host molecules and describes pathways for their survival, differentiation, and replication within the host cells. The book also delineates the role of inflammasomes and their activation in response to the protozoan parasite. The book discusses technological progress and machine learning-based modeling approaches to revisit parasitic infection from a non-conventional perspective. Collectively this book offers a comprehensive purview of concepts and paradigms in parasitic infection in the form of an updated yet discernible elucidation. 606 $aParasitology 606 $aInflammation 606 $aImmunology 606 $aParasitology 606 $aInflammation 606 $aImmunology 615 0$aParasitology. 615 0$aInflammation. 615 0$aImmunology. 615 14$aParasitology. 615 24$aInflammation. 615 24$aImmunology. 676 $a591.7857 702 $aMukherjee$b Budhaditya$f1955- 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910647788403321 996 $aPathobiology of Parasitic Protozoa: Dynamics and Dimensions$93313408 997 $aUNINA