LEADER 03579nam 2200505 450 001 9910647773103321 005 20230509073659.0 010 $a9783662667514$b(electronic bk.) 010 $z9783662667507 024 7 $a10.1007/978-3-662-66751-4 035 $a(MiAaPQ)EBC7191401 035 $a(Au-PeEL)EBL7191401 035 $a(CKB)26089880500041 035 $a(DE-He213)978-3-662-66751-4 035 $a(PPN)268210306 035 $a(EXLCZ)9926089880500041 100 $a20230509d2023 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEarly trauma as the origin of chronic inflammation $ea psychoneuroimmunological perspective /$fRainer H. Straub 205 $a1st ed. 2023. 210 1$aBerlin, Germany :$cSpringer,$d[2023] 210 4$dİ2023 215 $a1 online resource (267 pages) 311 08$aPrint version: Straub, Rainer H. Early Trauma As the Origin of Chronic Inflammation Berlin, Heidelberg : Springer Berlin / Heidelberg,c2023 9783662667507 320 $aIncludes bibliographical references. 327 $aLong shadows of early trauma - take a close look! -- What is childhood psychological trauma? -- Follow-up problems after early traumatic experiences -- Chronic immune activation -- Energy, early traumatic experiences and chronic immune activation. 330 $aThe aim of the book is to sensitize physicians and researchers to the important long-term health effects of early, persistent, and severe trauma. The author, an internist, rheumatologist, and basic researcher in psychoneuroimmunology, shows connections between adverse childhood experiences and typical adult sequelae. After early traumatic experiences and childhood stress, there is a higher incidence of mental illness, chronic pain, sleep disorders, dental problems, obesity, cardiovascular disease, asthma, diabetes mellitus and chronic inflammation. A selection of diseases unmistakably demonstrate the long-term consequences of early childhood trauma. These childhood experiences create a kind of long-term programming that has a negative effect in adulthood. From his psychoneuroimmunological perspective, Rainer Straub identifies four factors that link the brain to the immune system and are involved in chronic immune activation: direct connectors originating in the brain, indirect connectors functioning through hormonal and neuronal pathways, extracorporeal (the environmental factors) and pleiotropic (genetic factors) connectors. The author Prof. Rainer H. Straub, MD, is Professor of Experimental Medicine and is rheumatologist. He heads the Laboratory of Experimental Rheumatology and Neuroendocrine Immunology, Department of Internal Medicine at the University Hospital Regensburg. His nonfiction books "Understanding Aging, Fatigue, and Inflammation" (2018) and "Three Memories for the Body" (2020) have been published by Springer. The translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content. 606 $aInflammation 606 $aPsychic trauma in children 606 $aPsychoneuroimmunology 615 0$aInflammation. 615 0$aPsychic trauma in children. 615 0$aPsychoneuroimmunology. 676 $a616.0473 700 $aStraub$b Rainer H.$0895763 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 912 $a9910647773103321 996 $aEarly Trauma As the Origin of Chronic Inflammation$93016695 997 $aUNINA