LEADER 03579nam 2200505 450 001 9910647773103321 005 20230509073659.0 010 $a9783662667514$b(electronic bk.) 010 $z9783662667507 024 7 $a10.1007/978-3-662-66751-4 035 $a(MiAaPQ)EBC7191401 035 $a(Au-PeEL)EBL7191401 035 $a(CKB)26089880500041 035 $a(DE-He213)978-3-662-66751-4 035 $a(PPN)268210306 035 $a(EXLCZ)9926089880500041 100 $a20230509d2023 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEarly trauma as the origin of chronic inflammation $ea psychoneuroimmunological perspective /$fRainer H. Straub 205 $a1st ed. 2023. 210 1$aBerlin, Germany :$cSpringer,$d[2023] 210 4$dİ2023 215 $a1 online resource (267 pages) 311 08$aPrint version: Straub, Rainer H. Early Trauma As the Origin of Chronic Inflammation Berlin, Heidelberg : Springer Berlin / Heidelberg,c2023 9783662667507 320 $aIncludes bibliographical references. 327 $aLong shadows of early trauma - take a close look! -- What is childhood psychological trauma? -- Follow-up problems after early traumatic experiences -- Chronic immune activation -- Energy, early traumatic experiences and chronic immune activation. 330 $aThe aim of the book is to sensitize physicians and researchers to the important long-term health effects of early, persistent, and severe trauma. The author, an internist, rheumatologist, and basic researcher in psychoneuroimmunology, shows connections between adverse childhood experiences and typical adult sequelae. After early traumatic experiences and childhood stress, there is a higher incidence of mental illness, chronic pain, sleep disorders, dental problems, obesity, cardiovascular disease, asthma, diabetes mellitus and chronic inflammation. A selection of diseases unmistakably demonstrate the long-term consequences of early childhood trauma. These childhood experiences create a kind of long-term programming that has a negative effect in adulthood. From his psychoneuroimmunological perspective, Rainer Straub identifies four factors that link the brain to the immune system and are involved in chronic immune activation: direct connectors originating in the brain, indirect connectors functioning through hormonal and neuronal pathways, extracorporeal (the environmental factors) and pleiotropic (genetic factors) connectors. The author Prof. Rainer H. Straub, MD, is Professor of Experimental Medicine and is rheumatologist. He heads the Laboratory of Experimental Rheumatology and Neuroendocrine Immunology, Department of Internal Medicine at the University Hospital Regensburg. His nonfiction books "Understanding Aging, Fatigue, and Inflammation" (2018) and "Three Memories for the Body" (2020) have been published by Springer. The translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content. 606 $aInflammation 606 $aPsychic trauma in children 606 $aPsychoneuroimmunology 615 0$aInflammation. 615 0$aPsychic trauma in children. 615 0$aPsychoneuroimmunology. 676 $a616.0473 700 $aStraub$b Rainer H.$0895763 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 912 $a9910647773103321 996 $aEarly Trauma As the Origin of Chronic Inflammation$93016695 997 $aUNINA LEADER 01856oam 2200589zu 450 001 9910782061503321 005 20210721060416.0 010 $a1-282-16123-7 010 $a9786612161230 010 $a90-272-9650-2 035 $a(CKB)1000000000522223 035 $a(SSID)ssj0000129539 035 $a(PQKBManifestationID)11134166 035 $a(PQKBTitleCode)TC0000129539 035 $a(PQKBWorkID)10079705 035 $a(PQKB)11417035 035 $a(MiAaPQ)EBC622361 035 $a(EXLCZ)991000000000522223 100 $a20160829d2003 uy 101 0 $aeng 181 $ctxt 182 $cc 183 $acr 200 00$aContact Englishes of the Eastern Caribbean 210 31$a[Place of publication not identified]$cJ Benjamins$d2003 225 0 $aVarieties of English around the world Contact Englishes of the Eastern Caribbean 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a1-58811-363-9 311 $a90-272-4890-7 606 $aEnglish language$xVariation$zCaribbean Area 606 $aEnglish language$zCaribbean Area 606 $aCreole dialects, English$zCaribbean Area 606 $aLanguages in contact$zCaribbean Area 606 $aEnglish$2HILCC 606 $aLanguages & Literatures$2HILCC 606 $aEnglish Language$2HILCC 615 0$aEnglish language$xVariation 615 0$aEnglish language 615 0$aCreole dialects, English 615 0$aLanguages in contact 615 7$aEnglish 615 7$aLanguages & Literatures 615 7$aEnglish Language 676 $a427/.9729 700 $aAceto$b Michael$01512870 702 $aAceto$b Michael 702 $aWilliams$b Jeffrey P 801 0$bPQKB 906 $aBOOK 912 $a9910782061503321 996 $aContact Englishes of the Eastern Caribbean$93747049 997 $aUNINA