LEADER 03152nam 22005895 450 001 9910647770203321 005 20230131122522.0 010 $a981-19-3824-5 024 7 $a10.1007/978-981-19-3824-5 035 $a(MiAaPQ)EBC7188464 035 $a(Au-PeEL)EBL7188464 035 $a(CKB)26076434800041 035 $a(DE-He213)978-981-19-3824-5 035 $a(PPN)267810768 035 $a(EXLCZ)9926076434800041 100 $a20230131d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHandbook of Animal Models and its Uses in Cancer Research /$fedited by Surajit Pathak, Antara Banerjee, Atil Bisgin 205 $a1st ed. 2023. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2023. 215 $a1 online resource (1158 pages) 311 08$aPrint version: Pathak, Surajit Handbook of Animal Models and Its Uses in Cancer Research Singapore : Springer,c2023 9789811938238 320 $aIncludes bibliographical references and index. 327 $aModule 1_Animal Models in Cancer Research -- Animal Models in Cancer Research -- Module 2_ Therapeutic Cancer Research and Animal Models-Module 3_Alternative approaches for models of cancer research. 330 $aThis reference book compiles together different animal models in cancer research. It provides knowledge and a better understanding of the advancement of the molecular and cellular mechanisms associated with the progression, formation, and clinical results of various types of cancer from the evidence collected from animal models utilized for cancer research. It discusses animal models for screening anti-cancer drugs and exploration of gene therapy. It presents different methods used to construct cancer animal models and the progress of each animal model in tumor research. The book also highlights the applications of genetic engineering, including CRISP/Cas9, in designing and developing animal models for cancer research. Further, it discusses strategies for modeling animals for investigating growth, metastasis, tumor-associated inflammation and microenvironment, cancer stem cells, tumor heterogeneity, and therapeutic resistance. This book is s a valuable resource for basic and translational cancer researchers, clinicians, and health care. 606 $aCancer?Animal models 606 $aTumors?Classification 606 $aTumors?Immunological aspects 606 $aCancer Models 606 $aCancer Staging 606 $aTumour Immunology 615 0$aCancer?Animal models. 615 0$aTumors?Classification. 615 0$aTumors?Immunological aspects. 615 14$aCancer Models. 615 24$aCancer Staging. 615 24$aTumour Immunology. 676 $a616.027 702 $aBanerjee$b Antara 702 $aBisgin$b Atil 702 $aPathak$b Surajit 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910647770203321 996 $aHandbook of Animal Models and Its Uses in Cancer Research$93012315 997 $aUNINA