LEADER 02219nam 2200373 450 001 9910647495403321 005 20230328092414.0 035 $a(CKB)5680000000300321 035 $a(NjHacI)995680000000300321 035 $a(EXLCZ)995680000000300321 100 $a20230328d2022 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aEvolving Concepts in Insulin Resistance /$fedited by Marco Infante 210 1$aLondon :$cIntechOpen,$d2022. 210 4$dİ2022 215 $a1 online resource (ix, 190 pages) $cillustrations 311 $a1-80355-501-7 311 $a1-80355-502-5 327 $a1. The Insulin Journey in the Human Body -- 2. Insulin Receptor Isoforms in Physiology and Metabolic Disease -- 3. Molecular Mechanisms Involved in Insulin Resistance: Recent Updates and Future Challenges -- 4. Mechanisms of Insulin Resistance during Pregnancy -- 5. Dietary Activation of AMP-Activated Protein Kinase (AMPK) to Treat Insulin Resistance -- 6. Cardiac Natriuretic Peptide System: A Link between Adipose Tissue, Obesity, and Insulin Resistance -- 7. Berardinelli-Seip Syndrome: Report of an Old Case Successfully Treated with Anti-Glucocorticoid Therapy Followed by Bilateral Adrenalectomy. 330 $aOver the last decades, the growing prevalence of insulin resistance has dramatically contributed to the global epidemic of metabolic syndrome, obesity, type 2 diabetes mellitus, and cardiovascular disease. Therefore, there is an unmet need for novel nutritional and pharmacological strategies aimed to prevent or treat insulin resistance and its related comorbidities. This book presents a comprehensive overview of the pathophysiology and clinical consequences of insulin resistance in different settings, describing novel diagnostic biomarkers and molecular targets of this condition. 606 $aInsulin resistance 615 0$aInsulin resistance. 676 $a616.46207 702 $aInfante$b Marco 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910647495403321 996 $aEvolving Concepts in Insulin Resistance$93014206 997 $aUNINA