LEADER 02588nam 2200397 450 001 9910647495203321 005 20230328110739.0 035 $a(CKB)5680000000300323 035 $a(NjHacI)995680000000300323 035 $a(EXLCZ)995680000000300323 100 $a20230328d2023 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMolecular Docking $eRecent Advances /$fedited by Erman Salih I?stifli 210 1$aLondon :$cIntechOpen,$d2023. 210 4$dİ2023 215 $a1 online resource (xiii, 182 pages) $cillustrations 225 0 $aBiomedical engineering, ;$vVolume 15 311 $a1-80356-467-9 311 $a1-80356-468-7 327 $a1. Introductory Chapter: Molecular Docking-The Transition from the Micro Nature of Small Molecules to the Macro World -- 2. Fundamentals of Molecular Docking and Comparative Analysis of Protein-Small-Molecule Docking Approaches -- 3. Molecular Docking: Metamorphosis in Drug Discovery -- 4. Molecular Docking in the Study of Ligand-Protein Recognition: An Overview -- 5. Development of Nucleic Acid Targeting Molecules: Molecular Docking Approaches and Recent Advances -- 6. Repurposing Drugs as Potential Therapeutics for the SARS-Cov-2 Viral Infection: Automatizing a Blind Molecular Docking High-throughput Pipeline -- 7. N1-(3-(Trifluoromethyl)Phenyl) Isophthalamide Derivatives as Promising Inhibitors of Vascular Endothelial Growth Factor Receptor: Pharmacophore-Based Design, Docking, and MM-PBSA/MM-GBSA Binding Energy Estimation. 330 $aMolecular docking is a widely used bioinformatics method in biology, medicine, and biochemistry. This method, which can model interactions between different receptors and their various ligands at the molecular level, can represent intermolecular interactions at an unprecedented resolution that may not be achieved by classical experimental approaches. This book describes different aspects of this method that can reveal the intermolecular biochemical and biophysical interactions and the affinities of partner molecules to each other. It is designed for academics, students, and professionals interested in this technique. 517 $aMolecular Docking 606 $aPharmaceutical biotechnology 615 0$aPharmaceutical biotechnology. 676 $a615.19 702 $aI?stifli$b Erman Salih 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910647495203321 996 $aMolecular Docking$92157912 997 $aUNINA