LEADER 05744nam 2200793 a 450 001 9910819818403321 005 20200520144314.0 010 $a9781118503652 010 $a1118503651 010 $a9781299242630 010 $a1299242634 010 $a9781118503669 010 $a111850366X 010 $a9781118503676 010 $a1118503678 035 $a(CKB)2670000000336897 035 $a(EBL)1132797 035 $a(OCoLC)820665779 035 $a(SSID)ssj0000832859 035 $a(PQKBManifestationID)11465907 035 $a(PQKBTitleCode)TC0000832859 035 $a(PQKBWorkID)10899670 035 $a(PQKB)10617597 035 $a(MiAaPQ)EBC1132797 035 $a(Au-PeEL)EBL1132797 035 $a(CaPaEBR)ebr10667388 035 $a(CaONFJC)MIL455513 035 $a(PPN)190978279 035 $a(OCoLC)820665393 035 $a(FINmELB)ELB178501 035 $a(Perlego)1001720 035 $a(EXLCZ)992670000000336897 100 $a20121206d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 04$aThe chemistry of contrast agents in medical magnetic resonance imaging /$fedited by Andre? E. Merbach, Lothar Helm, E?va To?th 205 $a2nd ed. 210 $aHoboken, N.J. $cJohn Wiley & Sons Inc.$d2013 215 $a1 online resource (514 p.) 300 $aDescription based upon print version of record. 311 08$a9781119991762 311 08$a1119991765 320 $aIncludes bibliographical references and index. 327 $aCover; Title Page; Copyright; Contents; List of Contributors; Preface; Chapter 1 General Principles of MRI; 1.1 Introduction; 1.2 Theoretical basis of NMR; 1.2.1 Short description of NMR; 1.2.2 Relaxation times; 1.2.3 Saturation transfer; 1.2.4 Concept of localization by magnetic field gradients; 1.3 Principles of magnetic resonance imaging; 1.3.1 Spatial encoding; 1.4 MRI pulse sequences; 1.4.1 Definition; 1.4.2 k-Space trajectory; 1.4.3 Basic pulse sequences 327 $a1.5 Basic image contrast: Tissue characterization without injection of contrast agents (main contrast of an MRI sequence: Proton density (P), T_1 and T_2, T_2^*)1.5.1 Proton density weighting; 1.5.2 T1 weighting; 1.5.3 T2 weighting; 1.5.4 T2* weighting; 1.6 Main contrast agents; 1.6.1 Gadolinium (Gd) complex agents; 1.6.2 Iron oxide (IO) agents; 1.6.3 CEST agents; 1.7 Examples of specialized MRI pulse sequences for angiography (MRA); 1.7.1 Time of flight angiography: No contrast agent; 1.7.2 Angiography using intravascular contrast agent (Blood pool CA) injection; 1.7.3 DSC DCE MRI 327 $aReferencesChapter 2 Relaxivity of Gadolinium(III) Complexes: Theory and Mechanism; 2.1 Introduction; 2.2 Inner-sphere proton relaxivity; 2.2.1 Hydration number and hydration equilibria; 2.2.2 Gd-H distance; 2.2.3 Proton/water exchange; 2.2.4 Rotation; 2.3 Second- and outer-sphere relaxation; 2.4 Relaxivity and NMRD profiles; 2.4.1 Fitting of NMRD profiles; 2.4.2 Relaxivity of low-molecular-weight Gd(III) complexes; 2.4.3 Relaxivity of macromolecular MRI contrast agents; 2.4.4 Contrast agents optimized for application at high magnetic field; 2.5 Design of high relaxivity agents: Summary 327 $aReferencesChapter 3 Synthesis and Characterization of Ligands and their Gadolinium(III) Complexes; 3.1 Introduction-general requirements for the ligands and complexes; 3.2 Contrast agents employing linear polyamine scaffold; 3.2.1 Synthesis of linear polyamine backbone; 3.2.2 N-functionalization of linear polyamine scaffold; 3.3 Contrast agents employing cyclen scaffold; 3.3.1 Synthesis of the macrocyclic skeleton; 3.3.2 N-functionalization of macrocyclic scaffold; 3.4 Other types of ligands; 3.4.1 H4TRITA and related ligands; 3.4.2 H3PCTA and related ligands; 3.4.3 TACN derivatives 327 $a3.4.4 Ligands with HOPO coordinating arms and related groups3.4.5 H4AAZTA and related ligands; 3.5 Bifunctional ligands and their conjugations; 3.6 Synthesis and characterization of the Ln(III) complexes; 3.6.1 General synthetic remarks; 3.6.2 Characterization of the complexes; List of Abbreviations; References; Chapter 4 Stability and Toxicity of Contrast Agents; 4.1 Introduction; 4.2 Equilibrium calculations 327 $a4.2.1 Constants that characterize metal ligand interactions (protonation constants of the ligands, stability constants of the complexes, conditional stability constants, ligand selectivity, and concentration of free Gd^3+: pM) 330 $a"The second edition of The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging is a comprehensive treaty covering all aspects of production, use, operating mechanism and theory of these diagnostic agents used to produce high contrast images in MRI.It has been completed to now include recent developments on "classical" Gd-based and iron-oxide probes and chapters dedicated to the most significant advances in molecular imaging probes. Chemical Exchange Saturation Transfer is discussed, which is a novel means of generating MRI contrast"--$cProvided by publisher. 606 $aContrast-enhanced magnetic resonance imaging 606 $aMagnetic resonance imaging 615 0$aContrast-enhanced magnetic resonance imaging. 615 0$aMagnetic resonance imaging. 676 $a616.07/548 686 $aSCI078000$2bisacsh 701 $aHelm$b Lothar$01684287 701 $aMerbach$b Andre? E$01684288 701 $aTo?th$b E?va$0685600 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910819818403321 996 $aThe chemistry of contrast agents in medical magnetic resonance imaging$94055701 997 $aUNINA LEADER 03703nam 2201009z- 450 001 9910404090003321 005 20210211 010 $a3-03928-527-0 035 $a(CKB)4100000011302238 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/49437 035 $a(oapen)doab49437 035 $a(EXLCZ)994100000011302238 100 $a20202102d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aHistorical Acoustics: Relationships between People and Sound over Time 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (234 p.) 311 08$a3-03928-526-2 330 $aThis book is a collection of contributions to the Special Issue "Historical Acoustics: Relationships between People and Sound over Time". The research presented here aims to explore the origins of acoustics and examine the relationships that have evolved over the centuries between people and auditory phenomena. Sounds have indeed accompanied human civilizations since the beginning of time, helping them to make sense of the world and to shape their cultures. Several key topics emerged, such as the acoustics of historical worship buildings, the acoustics of sites of archaeological interest, the acoustics of historical opera houses, and the topic of soundscapes as cultural intangible heritage. The book, as a whole, reflects the vibrant research activity around the "acoustics of the past", which will hopefully be serve as a foundation for inspiring the future path of this discipline. 517 $aHistorical Acoustics 610 $aacoustic design 610 $aacoustic heritage 610 $aacoustic simulation 610 $aacoustics 610 $aAncestral Puebloan 610 $aancient Greek theatre 610 $aarchaeoacoustics 610 $aarchaeology 610 $aarcheoacoustics 610 $aarchitectural conservation 610 $aarchitectural heritage 610 $aarchives 610 $aBerlin Wall 610 $acathedral acoustics 610 $acave 610 $aChaco Canyon 610 $achoir space 610 $achurch acoustics 610 $aclarity 610 $aClassical Era 610 $acultural heritage 610 $adigital humanities 610 $aEDT 610 $ageneral's harangue 610 $aHagia Sophia 610 $aheritage acoustics 610 $ahistoric soundscapes 610 $ahistorical speeches 610 $ahistorical structures 610 $ahistory 610 $aJulius Caesar 610 $aLazarica church 610 $amedieval building 610 $amemorial 610 $amilitary history 610 $amusic 610 $an/a 610 $aopen-air performance space 610 $aopera house 610 $apolitical theater 610 $arestoration 610 $areverberation 610 $areverberation time 610 $aroom acoustics 610 $ascenery 610 $ashape optimisation 610 $asound 610 $asound mapping 610 $asoundscape survey 610 $asoundscapes 610 $aSpanish cathedrals 610 $aspeech intelligibility 610 $aStonehenge 610 $aSu?leymaniye Mosque 610 $atheatre 610 $aworship acoustics 610 $aYork Minster 700 $aAletta$b Francesco$4auth$01287635 702 $aKang$b Jian$4auth 906 $aBOOK 912 $a9910404090003321 996 $aHistorical Acoustics: Relationships between People and Sound over Time$93020238 997 $aUNINA LEADER 02688nam 22004693a 450 001 9910645965303321 005 20230830185920.0 010 $a9783985540181 010 $a3985540187 024 8 $ahttps://doi.org/10.5281/zenodo.5155544 035 $a(CKB)5460000000185152 035 $a(ScCtBLL)b2e46d6b-f719-41c4-b313-6fe973d6a247 035 $a(oapen)doab72385 035 $a(EXLCZ)995460000000185152 100 $a20211214i20212021 uu 101 0 $aeng 135 $auru|||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aAdvances in formal Slavic linguistics 2018$fLjudmila Geist, Hagen Pitsch, Jovana Gajic?, Andreas Blu?mel, Uwe Junghanns$hVolume 4 210 $cLanguage Science Press$d2021 210 1$aBerlin :$cLanguage Science Press,$d2021. 215 $a1 online resource (460 p.) 225 1 $aOpen Slavic Linguistics 330 $aAdvances in Formal Slavic Linguistics 2018 offers a selection of articles that were prepared on the basis of talks presented at the conference Formal Description of Slavic Languages (FDSL 13) or at the parallel Workshop on the Semantics of Noun Phrases, which were held on December 5-7, 2018, at the University of Go?ttingen. The volume covers a wide array of topics, such as situation relativization with adverbial clauses (causation, concession, counterfactuality, condition, and purpose), clause-embedding by means of a correlate, agreeing vs. transitive 'need' constructions, clitic doubling, affixation and aspect, evidentiality and mirativity, pragmatics coming with the particle li, uniqueness, definiteness, maximal interpretation (exhaustivity), kinds and subkinds, bare nominals, multiple determination, quantification, demonstratives, possessives, complex measure nouns, and the NP/DP parameter. The set of object languages comprises Russian, Czech, Polish, Bulgarian, Macedonian, Serbo-Croatian, and Torlak Serbian. The numerous topics addressed demonstrate the importance of Slavic linguistics. The original analyses prove that substantial progress has been made in major fields of research. 410 $aOpen Slavic Linguistics 606 $aLanguage Arts & Disciplines / Linguistics$2bisacsh 606 $aLanguage arts 615 7$aLanguage Arts & Disciplines / Linguistics 615 0$aLanguage arts. 702 $aGeist$b Ljudmila 702 $aPitsch$b Hagen 702 $aGajic?$b Jovana 702 $aBlu?mel$b Andreas 702 $aJunghanns$b Uwe 801 0$bScCtBLL 801 1$bScCtBLL 906 $aBOOK 912 $a9910645965303321 996 $aAdvances in formal Slavic linguistics 2018$93007479 997 $aUNINA