LEADER 02741nam 2200625Ia 450 001 9910643829203321 005 20230213211633.0 010 $a1-280-59065-3 010 $a9786613620484 010 $a0-470-71980-X 010 $a0-470-71745-9 035 $a(CKB)1000000000688017 035 $a(EBL)703822 035 $a(OCoLC)775868341 035 $a(SSID)ssj0000715279 035 $a(PQKBManifestationID)11454826 035 $a(PQKBTitleCode)TC0000715279 035 $a(PQKBWorkID)10700483 035 $a(PQKB)10713498 035 $a(MiAaPQ)EBC703822 035 $a(EXLCZ)991000000000688017 100 $a20720612d1971 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aPyrogens and fever$b[electronic resource] /$fedited by G. E. W. Wolstenholme and Joan Birch 210 $aEdinburgh $cChurchill Livingstone$d1971 215 $a1 online resource (248 p.) 225 1 $aNovartis Foundation Symposia 300 $a"A Ciba Foundation symposium." 311 $a0-470-66285-9 311 $a0-7000-1504-3 320 $aIncludes bibliographical references and index. 327 $aPYROGENS AND FEVER; Contents; Note on terminology; Chairman's opening remarks; Some physiological and clinical aspects of pyrogens; Discussion; Production, chemistry and properties of bacterial pyrogens and endotoxins; Discussion; The significant immunological features of bacterial endotoxins; Discussion; Purification of an endogenous pyrogen, with an appendix on assay methods; Discussion; Role of leucocytes in fever; Discussion; Mechanism of action of pyrogenic and antipyretic steroids in vitro; Discussion; On the mechanism of action of pyrogens; Discussion 327 $aHypothalamic mechanisms of pyrogen action in the cat and monkeyDiscussion; Relevance of experimental observations to pyrexia in clinical situations; Discussion; The mechanism of action of antipyretics; Discussion; Pharmaceutical aspects of pyrogens in hospital and industry; Discussion; The dilemma of quantitation in the test for pyrogens; Discussion; General discussion; Author index; Subject index 410 0$aNovartis Foundation Symposia 606 $aPyrogens$vCongresses 606 $aFever$vCongresses 615 0$aPyrogens 615 0$aFever 676 $a616.9 676 $a616.926 701 $aWolstenholme$b G. E. W$g(Gordon Ethelbert Ward)$063039 701 $aBirch$b Joan$0896374 712 02$aCiba Foundation. 712 12$aSymposium on Pyrogens and Fever 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910643829203321 996 $aPyrogens and fever$92002563 997 $aUNINA