LEADER 03783nam 2200961z- 450 001 9910639998103321 005 20231214132846.0 010 $a3-0365-5887-X 035 $a(CKB)5470000001633372 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/95781 035 $a(EXLCZ)995470000001633372 100 $a20202301d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPathophysiology of Spinal Cord Injury (SCI) 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (258 p.) 311 $a3-0365-5888-8 330 $aSpinal cord injury (SCI) leads to paralysis, sensory, and autonomic nervous system dysfunctions. However, the pathophysiology of SCI is complex, and not limited to the nervous system. Indeed, several other organs and tissue are also affected by the injury, directly or not, acutely or chronically, which induces numerous health complications. Although a lot of research has been performed to repair motor and sensory functions, SCI-induced health issues are less studied, although they represent a major concern among patients. There is a gap of knowledge in pre-clinical models studying these SCI-induced health complications that limits translational applications in humans. This reprint describes several aspects of the pathophysiology of spinal cord injuries. This includes, but is not limited to, the impact of SCI on cardiovascular and respiratory functions, bladder and bowel function, autonomic dysreflexia, liver pathology, metabolic syndrome, bones and muscles loss, and cognitive functions. 517 $aPathophysiology of Spinal Cord Injury 606 $aMedicine$2bicssc 606 $aNeurosciences$2bicssc 610 $amicturition 610 $aexternal urethral sphincter 610 $aspinal cord injury 610 $aserotonin 610 $aelectromyogram 610 $afecal microbiota transplant 610 $ainflammation 610 $aanxiety 610 $arehabilitation 610 $aautonomic dysreflexia 610 $aimmune dysfunction 610 $aSCI-IDS 610 $aprimary afferents 610 $anociceptor 610 $areach-to-grasp 610 $aforelimb function 610 $aupper extremity function 610 $acardiovascular 610 $acontusion 610 $aneuroplasticity 610 $aosteopenia 610 $abone loss 610 $arecovery of function 610 $amonoamines 610 $aGABA 610 $aneuromodulation 610 $apain 610 $aspasticity 610 $aionic plasticity 610 $arepetitive transcranial magnetic stimulation 610 $aphrenic motor network 610 $amotoneuron excitability 610 $adiaphragm muscle 610 $aspinal cord injury severity 610 $acardiometabolic disease 610 $aliver and cardiac dysfunctions 610 $afibrosis 610 $apathophysiology 610 $aoxidative stress 610 $acontusion model 610 $arespiratory function 610 $adiaphragmatic activity 610 $aphrenic motoneurons 610 $aneuroinflammation 610 $acytokines 610 $atumor necrosis factor 610 $aimmune cells 610 $amicroglia 615 7$aMedicine 615 7$aNeurosciences 700 $aGeoffroy$b Cédric$4edt$01302850 702 $aAlilain$b Warren$4edt 702 $aGeoffroy$b Cédric$4oth 702 $aAlilain$b Warren$4oth 906 $aBOOK 912 $a9910639998103321 996 $aPathophysiology of Spinal Cord Injury (SCI)$93026691 997 $aUNINA