LEADER 05297nam 2201429z- 450 001 9910639996703321 005 20231214132843.0 010 $a3-0365-6099-8 035 $a(CKB)5470000001633386 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/95875 035 $a(EXLCZ)995470000001633386 100 $a20202301d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMicro/Nanofluidic and Lab-on-a-Chip Devices for Biomedical Applications 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (232 p.) 311 $a3-0365-6100-5 330 $aRecently, microfluidic, nanofluidic and lab-on-a-chip devices have gained particular attention in biomedical applications. Due to their advantages, such as miniaturization, versatility, ease of use, cost-effectiveness, and the potential to replace animal models for drug development and testing, these devices hold tremendous potential to revolutionize the research of more effective treatments for several diseases that threaten human life. With integrated biosensors, these devices allow the development and design of micro- and nanoparticles to be studied in detail, modelling human physiology, investigating the molecular and cellular mechanisms underlying disease formation and progression, and gaining insights into the performance and long-term effects of responsive drug delivery nanocarriers. This Special Issue gathered research papers, and review articles focusing on novel microfluidic, nanofluidic and lab-on-a-chip devices for biomedical applications, addressing all steps related to fabrication, biosensor integration and development, characterization, numerical simulations and validation of the devices, optimization and, the translation of these devices from research labs to industry settings. 606 $aMedicine$2bicssc 610 $aprotein biomarker 610 $amicroarray 610 $amicrofluidic cassette 610 $amultiplex measurement 610 $aimmunoassay 610 $apoint-of-care testing 610 $amicrofluidic device 610 $asmall intestine 610 $aex vivo 610 $ahistology 610 $aembedded resin 610 $asectioning 610 $apeptide biosensor 610 $alab-on-a-chip 610 $alabel-free detection 610 $apeptide aptamers 610 $aprotein biomarkers 610 $amicrofluidic biochip 610 $atroponin T 610 $acomputational simulations 610 $adrug discovery 610 $aorgan-on-a-chip 610 $amicrofluidic devices 610 $apreclinical models 610 $anumerical simulations 610 $aautomation 610 $anon-enzymatic 610 $aDNA amplification 610 $aL-DNA 610 $amicrofluidic 610 $afluorescence 610 $apaper microfluidics 610 $asweat 610 $asensing 610 $ahydrogels 610 $alactate 610 $aosmotic pumping 610 $aevaporation 610 $acapillary 610 $awicking 610 $abiochemical assay 610 $amicrofluidics 610 $acell trap 610 $aRBC 610 $aevolutionary algorithm 610 $agenerative design 610 $aartificial intelligence 610 $aorgan-on-chip 610 $aliver-on-chip 610 $aliver disease 610 $amulti-level microfluidic device 610 $alive cell imaging 610 $along-term microscopy imaging 610 $afocus drifting 610 $aimmersion oil viscosity 610 $abacterial population dynamics 610 $asingle-cell studies 610 $aE. coli 610 $amother machine 610 $acomputational fluid dynamics 610 $acancer-on-chip 610 $axenograft 610 $acolorectal cancer 610 $apharmacodynamics 610 $apharmacokinetics 610 $adrug efficacy 610 $aoxaliplatin 610 $amicrofabrication 610 $amicrophysiological system 610 $abiophysical stimuli 610 $abiochemical stimuli 610 $ain vitro cell culture 610 $acortical neurons 610 $ahippocampal neurons 610 $aelectrical stimulation 610 $aMicro-Electrode Arrays 610 $aengineered neuronal networks 610 $apolydimethylsiloxane 610 $amicrochannels 610 $ain vivo micro bioreactor 610 $aadditive manufacturing 610 $apoly-(ethylene glycol)-diacrylate 610 $abiocompatibility 610 $aCOVID-19 610 $adiagnosis 610 $aimage analysis 610 $aPCR 610 $aSARS-CoV-2 615 7$aMedicine 700 $aCarvalho$b Violeta$4edt$01302053 702 $aTeixeira$b Senhorinha de Fa?tima Capela Fortunas$4edt 702 $aRibeiro$b Joa?o$4edt 702 $aCarvalho$b Violeta$4oth 702 $aTeixeira$b Senhorinha de Fa?tima Capela Fortunas$4oth 702 $aRibeiro$b Joa?o$4oth 906 $aBOOK 912 $a9910639996703321 996 $aMicro$93026065 997 $aUNINA LEADER 03731nam 22009493a 450 001 9910367566403321 005 20250203235437.0 010 $a9783039213023 010 $a3039213024 024 8 $a10.3390/books978-3-03921-302-3 035 $a(CKB)4100000010106082 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/62533 035 $a(ScCtBLL)014a566d-f0b9-4caf-b6ff-3e85ec7cc888 035 $a(OCoLC)1163851468 035 $a(oapen)doab62533 035 $a(EXLCZ)994100000010106082 100 $a20250203i20192019 uu 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aWater-Worked Bedload : $eHydrodynamic and Mass Transport /$fPawe? M. Rowi?ski, Subhasish Dey 210 $cMDPI - Multidisciplinary Digital Publishing Institute$d2019 210 1$aBasel, Switzerland :$cMDPI,$d2019. 215 $a1 electronic resource (152 p.) 311 08$a9783039213016 311 08$a3039213016 330 $aThe state-of-the-art in water-worked bed hydraulics can only be examined through a careful exploration of the experimental (both laboratory and field) results via theoretical development. This book is primarily focused on the research aspects that involve a comprehensive knowledge of sediment dynamics in turbulent flows, as the most up-to-date research findings in the field are presented. It begins with two reviews on bedload transport and water-work bed experimental studies. The sediment dynamics is then analyzed from a classical perspective by applying the mean bed shear approach and additionally incorporating a statistical description for the role of turbulence. The work finally examines the local scour problems at hydraulic structures and results from field studies. It is intended as a course guide for field professionals, keeping up with modern technological developments. Therefore, as a simple prerequisite, readers should have a basic knowledge of hydraulics to an undergraduate level. 610 $arisk assessment 610 $aheavy metals 610 $asand waves 610 $ascour depth 610 $ain-stream structures 610 $abackwater effect 610 $afriction factor 610 $anatural sandy bed river 610 $amorphology 610 $aturbulent flow 610 $asediment 610 $aflood 610 $aspur dike 610 $awater reservoir 610 $alocal bed shear stress 610 $agravel-bed stream 610 $alogarithmic law of the wall 610 $aenvironmental variables 610 $amountain stream 610 $aexperiments 610 $ascour holes 610 $adrag-reducing flows 610 $aflow type 610 $aThree Gorges Reservoir 610 $ahysteresis 610 $aacoustic Doppler velocimeter 610 $acheck dam 610 $abedload 610 $agranular beds 610 $abed-load transport 610 $aaquatic plants 610 $aflow velocity measurements 610 $agroyne type 610 $afluvial hydraulics 610 $agroyne field 610 $aflow resistance 610 $awater-worked gravel bed 610 $aMountain River 610 $aaquatic plant biomechanics 610 $avon Ka?rma?n parameter ? 610 $abed shear stress 610 $ariver morphology 610 $ariver 610 $aturbulent kinetic energy 610 $ascour 700 $aRowi?ski$b Pawe? 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