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010   $a9783031129742$b(electronic bk.)
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024 7 $a10.1007/978-3-031-12974-2
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035   $a(DE-He213)978-3-031-12974-2
035   $a(OCoLC)1369656710
035   $a(BIP)084962175
035   $a(PPN)267807406
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101 0 $aeng
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181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aCancer Stem Cell Markers and Related Network Pathways /$fedited by Shihori Tanabe
205   $a1st ed. 2022.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2022.
215   $a1 online resource (163 pages)
225 1 $aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v1393
311 08$aPrint version: Tanabe, Shihori Cancer Stem Cell Markers and Related Network Pathways Cham : Springer International Publishing AG,c2023 9783031129735 
327   $a1. Epithelial-mesenchymal transition and cancer stem cells -- 2. The transcription factors Zeb1 and Snail induce cell malignancy and can-cer stem cell phenotype in prostate cells, increasing androgen synthesis ca-pacity and therapy resistance -- 3. ERBB signaling pathway in cancer stem cells -- 4. Functional and molecular characters of cancer stem cells through devel-opment to establishment -- 5. Microenvironment in cancer stem cells -- 6. Cancer stem cells contribute to drug resistance in multiple different ways -- 7. Abnormal glycosylation in cancer cells and cancer stem cells as a thera-peutic target.
330   $aThis book entitled ?Cancer Stem Cell Markers and Related Network Path-ways? is about cancer stem cell (CSC) markers and the molecular network pathways. CSCs play an important role in the cancer drug resistance, metastasis and recurrence. Epithelial-mesenchymal transition (EMT) is closely related to CSC phenotype. This book covers various aspects of the molecular networks related to CSCs including the important phenotypic change such as EMT. Readers will discover the importance of the identification of CSC markers and EMT-related molecules in CSC network pathways. The CSC signaling pathways and EMT molecular network pathways attract researchers in the field to define the cancer therapeutic targets. Cancer environment is important in the acquisition of CSC phenotype in cells. The revealing of this CSC mystery is across 7 chapters. The topic of this book is particularly relevant to research in thefield of cancer and stem cells, as well as the network pathways. We hope that this book helps the readers to be interested in understanding why the CSC concept is important and attractive.
410  0$aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v1393
606   $aMedicine$xResearch
606   $aBiology$xResearch
606   $aMedical genetics
606   $aMedical microbiology
606   $aBiomedical Research
606   $aBiomedical Research
606   $aMedical Genetics
606   $aMedical Microbiology
615  0$aMedicine$xResearch.
615  0$aBiology$xResearch.
615  0$aMedical genetics.
615  0$aMedical microbiology.
615 14$aBiomedical Research.
615 24$aBiomedical Research.
615 24$aMedical Genetics.
615 24$aMedical Microbiology.
676   $a610.28
676   $a616.99407582
702   $aTanabe$b Shihori$4edt
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912   $a9910639878103321
996   $aCancer Stem Cell Markers and Related Network Pathways$93003347
997   $aUNINA