LEADER 03728nam 2200625 450 001 9910639878103321 005 20240228160751.0 010 $a9783031129742$b(electronic bk.) 010 $z9783031129735 024 7 $a10.1007/978-3-031-12974-2 035 $a(MiAaPQ)EBC7167832 035 $a(Au-PeEL)EBL7167832 035 $a(CKB)25936425400041 035 $a(DE-He213)978-3-031-12974-2 035 $a(OCoLC)1369656710 035 $a(BIP)084962175 035 $a(PPN)267807406 035 $a(EXLCZ)9925936425400041 100 $a20230506d2023 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aCancer stem cell markers and related network pathways /$fedited by Shihori Tanabe 205 $a1st ed. 2022. 210 1$aCham, Switzerland :$cSpringer,$d[2023] 210 4$d©2023 215 $a1 online resource (163 pages) 225 1 $aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v1393 311 08$aPrint version: Tanabe, Shihori Cancer Stem Cell Markers and Related Network Pathways Cham : Springer International Publishing AG,c2023 9783031129735 327 $a1. Epithelial-mesenchymal transition and cancer stem cells -- 2. The transcription factors Zeb1 and Snail induce cell malignancy and can-cer stem cell phenotype in prostate cells, increasing androgen synthesis ca-pacity and therapy resistance -- 3. ERBB signaling pathway in cancer stem cells -- 4. Functional and molecular characters of cancer stem cells through devel-opment to establishment -- 5. Microenvironment in cancer stem cells -- 6. Cancer stem cells contribute to drug resistance in multiple different ways -- 7. Abnormal glycosylation in cancer cells and cancer stem cells as a thera-peutic target. 330 $aThis book entitled ?Cancer Stem Cell Markers and Related Network Path-ways? is about cancer stem cell (CSC) markers and the molecular network pathways. CSCs play an important role in the cancer drug resistance, metastasis and recurrence. Epithelial-mesenchymal transition (EMT) is closely related to CSC phenotype. This book covers various aspects of the molecular networks related to CSCs including the important phenotypic change such as EMT. Readers will discover the importance of the identification of CSC markers and EMT-related molecules in CSC network pathways. The CSC signaling pathways and EMT molecular network pathways attract researchers in the field to define the cancer therapeutic targets. Cancer environment is important in the acquisition of CSC phenotype in cells. The revealing of this CSC mystery is across 7 chapters. The topic of this book is particularly relevant to research in the field of cancer and stem cells, as well as the network pathways. We hope that this book helps the readers to be interested in understanding why the CSC concept is important and attractive. 410 0$aAdvances in Experimental Medicine and Biology,$x2214-8019 ;$v1393 606 $aBiochemical markers 606 $aStem cells 606 $aCèl·lules mare$2thub 606 $aMarcadors bioquímics$2thub 606 $aCitodiagnòstic$2thub 608 $aLlibres electrònics$2thub 610 $aInternal Medicine 610 $aMedical 615 0$aBiochemical markers. 615 0$aStem cells. 615 7$aCèl·lules mare 615 7$aMarcadors bioquímics 615 7$aCitodiagnòstic 676 $a610.28 702 $aTanabe$b Shihori$4edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 912 $a9910639878103321 996 $aCancer Stem Cell Markers and Related Network Pathways$93003347 997 $aUNINA